커큐민 관련 과민성 대장 증후군(IBS)
C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.소규모 RCT에서 IBS 증상 개선을 시사합니다. 항염 기전은 타당하나 강력한 권장을 위한 근거는 불충분합니다.
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C
결론
소규모 RCT에서 IBS 증상 개선을 시사합니다. 항염 기전은 타당하나 강력한 권장을 위한 근거는 불충분합니다.
Key Study Findings
Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)
Review
Curcumin in Inflammatory Complications: Therapeutic Applications and Clinical Evidence.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Review of curcumin in inflammatory complications
Systematic Review
n=1123
Double-blind
Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic …
Dose: None
vs: Placebo/control
Outcome: Depression and anxiety in chronic diseases
효과: SMD -0.65 [-1.16, -0.13] depression; SMD -0.22 [-0
0.01 (both)
대상 집단: Adults with chronic diseases and depression/anxiety (15 RCTs)
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
vs: Various
Outcome: IBS symptom improvement
효과: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
대상 집단: Adult IBS patients
Review
Natural Remedies for Irritable Bowel Syndrome: A Comprehensive Review of Herbal-Based Therapies.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Review of herbal remedies for IBS
Systematic Review
A systematic review of the efficacy and safety of turmeric in the treatment of digestive …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: IBS patients
Key Statistics
2
연구
200
참여자
↑
Positive
C
등급
Referenced Papers
Nutrients
2026
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
Nutrition reviews
2025
10 인용
Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic review of mechanistic and clinical …
Systematic Review
Frontiers in pharmacology
2025
4 인용
International journal of …
2025
2 인용
Natural Remedies for Irritable Bowel Syndrome: A Comprehensive Review of Herbal-Based Therapies.
Review
International journal of …
2025
1 인용
A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders.
Systematic Review
Phytotherapy research : …
2024
10 인용
Nutrients
2024
6 인용
[Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review].
Systematic Review
Zeitschrift fur Gastroenterologie
2024
3 인용
CNS & neurological …
2023
24 인용
Frontiers in microbiology
2023
11 인용
International journal of …
2023
9 인용
Nutrients
2022
16 인용
Iranian journal of …
2022
12 인용
Molecules (Basel, Switzerland)
2021
85 인용
BMC complementary medicine …
2021
56 인용
A Systematic Review of the Clinical Use of Curcumin for the Management of Gastrointestinal Diseases.
Systematic Review
Advances in experimental …
2021
8 인용
Nutrition research (New …
2020
42 인용
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Meta-Analysis
Complementary therapies in …
2020
34 인용
Journal of ethnopharmacology
2019
83 인용
Current gastroenterology reports
2019
17 인용
The American journal …
2019
15 인용
Journal of clinical …
2019
3 인용
Journal of clinical …
2018
75 인용
Annals of gastroenterology
2018
25 인용
Medical principles and …
2017
45 인용
Phytotherapy research : …
2017
26 인용
Current gastroenterology reports
2017
16 인용
The Medical clinics …
2017
9 인용
Journal of gastrointestinal …
2016
96 인용
Current gastroenterology reports
2016
30 인용
Metabolic brain disease
2015
62 인용
Voprosy pitaniia
2015
8 인용
The AAPS journal
2013
1866 인용
Molecular nutrition & …
2013
395 인용
Voprosy pitaniia
2013
Clinics (Sao Paulo, …
2010
47 인용
Indian journal of …
2010
14 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 500-1,500 mg/day with piperine (black pepper extract) for absorption
- ibssupport:
- 500-1,000 mg/day
- ucmaintenance:
- 2,000 mg/day (1 g twice daily) as adjunct to mesalamine
상한량: Well-tolerated up to 8 g/day in clinical trials (most studies use 1-2 g/day)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 1123 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| Peppermint oil, STW-5, psyllium, others | -- | Positive | -- |
| 200 mg | 8 weeks | Positive | -- |
권장 복용 시간: With meals containing fat and black pepper for enhanced absorption
Safety & Side Effects
보고된 부작용
- ⚠ GI discomfort (nausea, diarrhea, abdominal pain) at high doses
- ⚠ Yellow staining of skin/teeth with topical/oral contact
- ⚠ Increased gallbladder contractions (avoid with gallstones or bile duct obstruction)
- ⚠ Iron chelation (may reduce iron absorption at very high doses)
알려진 상호작용
- ● Anticoagulants (curcumin has antiplatelet properties; may increase bleeding risk)
- ● Chemotherapy agents (curcumin may alter drug metabolism via CYP enzyme inhibition)
- ● Sulfasalazine (additive anti-inflammatory effect — may be beneficial in IBD)
- ● Iron supplements (curcumin may chelate iron; space dosing)
- ● Piperine/black pepper (enhances curcumin bioavailability by 2,000% — commonly co-administered)
일일 최대 섭취 허용량: Well-tolerated up to 8 g/day in clinical trials (most studies use 1-2 g/day)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 커큐민 help with 과민성 대장 증후군(IBS)?
Based on 2 studies with 200 participants, there is limited but promising evidence that 커큐민 may support 과민성 대장 증후군(IBS) management. Our evidence grade is C (Some Evidence).
How much 커큐민 should I take for 과민성 대장 증후군(IBS)?
Studies have used various dosages. A commonly studied range is 500-1,500 mg/day with piperine (black pepper extract) for absorption. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 커큐민?
Reported side effects may include GI discomfort (nausea, diarrhea, abdominal pain) at high doses, Yellow staining of skin/teeth with topical/oral contact, Increased gallbladder contractions (avoid with gallstones or bile duct obstruction), Iron chelation (may reduce iron absorption at very high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 커큐민 and 과민성 대장 증후군(IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 과민성 대장 증후군(IBS)
커큐민 다른 건강 상태에 대한 근거
References
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