Curcumin لـ Irritable Bowel Syndrome (IBS)
C الأدلة أدلة محدودة من دراسات صغيرة، غير أن ثمة بعض الإشارات الإيجابية.Small RCTs suggest improvement in IBS symptoms. Anti-inflammatory mechanism plausible but evidence insufficient for strong recommendation.
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C
الخلاصة
Small RCTs suggest improvement in IBS symptoms. Anti-inflammatory mechanism plausible but evidence insufficient for strong recommendation.
Key Study Findings
Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)
Review
Curcumin in Inflammatory Complications: Therapeutic Applications and Clinical Evidence.
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: Review of curcumin in inflammatory complications
Systematic Review
n=1123
Double-blind
Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic …
Dose: None
مقابل: Placebo/control
Outcome: Depression and anxiety in chronic diseases
التأثير: SMD -0.65 [-1.16, -0.13] depression; SMD -0.22 [-0
0.01 (both)
المجتمع المدروس: Adults with chronic diseases and depression/anxiety (15 RCTs)
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
مقابل: Various
Outcome: IBS symptom improvement
التأثير: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
المجتمع المدروس: Adult IBS patients
Review
Natural Remedies for Irritable Bowel Syndrome: A Comprehensive Review of Herbal-Based Therapies.
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: Review of herbal remedies for IBS
Systematic Review
A systematic review of the efficacy and safety of turmeric in the treatment of digestive …
Dose: None
مقابل: None
Outcome: None
التأثير: None
None
المجتمع المدروس: IBS patients
Key Statistics
2
الدراسات
200
المشاركون
↑
Positive
C
التقييم
Referenced Papers
Nutrients
2026
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
Nutrition reviews
2025
10 اقتباسات
Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic review of mechanistic and clinical …
Systematic Review
Frontiers in pharmacology
2025
4 اقتباسات
International journal of …
2025
2 اقتباسات
Natural Remedies for Irritable Bowel Syndrome: A Comprehensive Review of Herbal-Based Therapies.
Review
International journal of …
2025
1 اقتباسات
A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders.
Systematic Review
Phytotherapy research : …
2024
10 اقتباسات
Nutrients
2024
6 اقتباسات
[Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review].
Systematic Review
Zeitschrift fur Gastroenterologie
2024
3 اقتباسات
CNS & neurological …
2023
24 اقتباسات
Frontiers in microbiology
2023
11 اقتباسات
International journal of …
2023
9 اقتباسات
Nutrients
2022
16 اقتباسات
Iranian journal of …
2022
12 اقتباسات
Molecules (Basel, Switzerland)
2021
85 اقتباسات
BMC complementary medicine …
2021
56 اقتباسات
A Systematic Review of the Clinical Use of Curcumin for the Management of Gastrointestinal Diseases.
Systematic Review
Advances in experimental …
2021
8 اقتباسات
Nutrition research (New …
2020
42 اقتباسات
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Meta-Analysis
Complementary therapies in …
2020
34 اقتباسات
Journal of ethnopharmacology
2019
83 اقتباسات
Current gastroenterology reports
2019
17 اقتباسات
The American journal …
2019
15 اقتباسات
Journal of clinical …
2019
3 اقتباسات
Journal of clinical …
2018
75 اقتباسات
Annals of gastroenterology
2018
25 اقتباسات
Medical principles and …
2017
45 اقتباسات
Phytotherapy research : …
2017
26 اقتباسات
Current gastroenterology reports
2017
16 اقتباسات
The Medical clinics …
2017
9 اقتباسات
Journal of gastrointestinal …
2016
96 اقتباسات
Current gastroenterology reports
2016
30 اقتباسات
Metabolic brain disease
2015
62 اقتباسات
Voprosy pitaniia
2015
8 اقتباسات
The AAPS journal
2013
1866 اقتباسات
Molecular nutrition & …
2013
395 اقتباسات
Voprosy pitaniia
2013
Clinics (Sao Paulo, …
2010
47 اقتباسات
Indian journal of …
2010
14 اقتباسات
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
الجرعات الشائعة
- general:
- 500-1,500 mg/day with piperine (black pepper extract) for absorption
- ibssupport:
- 500-1,000 mg/day
- ucmaintenance:
- 2,000 mg/day (1 g twice daily) as adjunct to mesalamine
الحد الأعلى: Well-tolerated up to 8 g/day in clinical trials (most studies use 1-2 g/day)
الجرعات المدروسة في الأبحاث
| الجرعة | المدة | التأثير | ن |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 1123 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| Peppermint oil, STW-5, psyllium, others | -- | Positive | -- |
| 200 mg | 8 weeks | Positive | -- |
أفضل وقت للتناول: With meals containing fat and black pepper for enhanced absorption
Safety & Side Effects
الآثار الجانبية المُبلّغ عنها
- ⚠ GI discomfort (nausea, diarrhea, abdominal pain) at high doses
- ⚠ Yellow staining of skin/teeth with topical/oral contact
- ⚠ Increased gallbladder contractions (avoid with gallstones or bile duct obstruction)
- ⚠ Iron chelation (may reduce iron absorption at very high doses)
التفاعلات المعروفة
- ● Anticoagulants (curcumin has antiplatelet properties; may increase bleeding risk)
- ● Chemotherapy agents (curcumin may alter drug metabolism via CYP enzyme inhibition)
- ● Sulfasalazine (additive anti-inflammatory effect — may be beneficial in IBD)
- ● Iron supplements (curcumin may chelate iron; space dosing)
- ● Piperine/black pepper (enhances curcumin bioavailability by 2,000% — commonly co-administered)
الحد الأقصى المسموح به: Well-tolerated up to 8 g/day in clinical trials (most studies use 1-2 g/day)
استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.
Frequently Asked Questions
Does Curcumin help with Irritable Bowel Syndrome (IBS)?
Based on 2 studies with 200 participants, there is limited but promising evidence that Curcumin may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Curcumin should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 500-1,500 mg/day with piperine (black pepper extract) for absorption. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Curcumin?
Reported side effects may include GI discomfort (nausea, diarrhea, abdominal pain) at high doses, Yellow staining of skin/teeth with topical/oral contact, Increased gallbladder contractions (avoid with gallstones or bile duct obstruction), Iron chelation (may reduce iron absorption at very high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Curcumin and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
Related Evidence
مكونات أخرى لـ Irritable Bowel Syndrome (IBS)
Curcumin لحالات أخرى
References
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