Curcumin для Irritable Bowel Syndrome (IBS)
C Доказательства Доказательства ограничены небольшими исследованиями, однако имеются некоторые положительные сигналы.Small RCTs suggest improvement in IBS symptoms. Anti-inflammatory mechanism plausible but evidence insufficient for strong recommendation.
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C
Итог
Small RCTs suggest improvement in IBS symptoms. Anti-inflammatory mechanism plausible but evidence insufficient for strong recommendation.
Key Study Findings
Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)
Review
Curcumin in Inflammatory Complications: Therapeutic Applications and Clinical Evidence.
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: Review of curcumin in inflammatory complications
Systematic Review
n=1123
Double-blind
Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic …
Dose: None
или: Placebo/control
Outcome: Depression and anxiety in chronic diseases
Эффект: SMD -0.65 [-1.16, -0.13] depression; SMD -0.22 [-0
0.01 (both)
Популяция: Adults with chronic diseases and depression/anxiety (15 RCTs)
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
или: Various
Outcome: IBS symptom improvement
Эффект: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
Популяция: Adult IBS patients
Review
Natural Remedies for Irritable Bowel Syndrome: A Comprehensive Review of Herbal-Based Therapies.
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: Review of herbal remedies for IBS
Systematic Review
A systematic review of the efficacy and safety of turmeric in the treatment of digestive …
Dose: None
или: None
Outcome: None
Эффект: None
None
Популяция: IBS patients
Key Statistics
2
Исследования
200
Участники
↑
Positive
C
Оценка
Referenced Papers
Nutrients
2026
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
Nutrition reviews
2025
10 цитирований
Potential therapeutic benefits of curcumin in depression or anxiety induced by chronic diseases: a systematic review of mechanistic and clinical …
Systematic Review
Frontiers in pharmacology
2025
4 цитирований
International journal of …
2025
2 цитирований
Natural Remedies for Irritable Bowel Syndrome: A Comprehensive Review of Herbal-Based Therapies.
Review
International journal of …
2025
1 цитирований
A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders.
Systematic Review
Phytotherapy research : …
2024
10 цитирований
Nutrients
2024
6 цитирований
[Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review].
Systematic Review
Zeitschrift fur Gastroenterologie
2024
3 цитирований
CNS & neurological …
2023
24 цитирований
Frontiers in microbiology
2023
11 цитирований
International journal of …
2023
9 цитирований
Nutrients
2022
16 цитирований
Iranian journal of …
2022
12 цитирований
Molecules (Basel, Switzerland)
2021
85 цитирований
BMC complementary medicine …
2021
56 цитирований
A Systematic Review of the Clinical Use of Curcumin for the Management of Gastrointestinal Diseases.
Systematic Review
Advances in experimental …
2021
8 цитирований
Nutrition research (New …
2020
42 цитирований
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Meta-Analysis
Complementary therapies in …
2020
34 цитирований
Journal of ethnopharmacology
2019
83 цитирований
Current gastroenterology reports
2019
17 цитирований
The American journal …
2019
15 цитирований
Journal of clinical …
2019
3 цитирований
Journal of clinical …
2018
75 цитирований
Annals of gastroenterology
2018
25 цитирований
Medical principles and …
2017
45 цитирований
Phytotherapy research : …
2017
26 цитирований
Current gastroenterology reports
2017
16 цитирований
The Medical clinics …
2017
9 цитирований
Journal of gastrointestinal …
2016
96 цитирований
Current gastroenterology reports
2016
30 цитирований
Metabolic brain disease
2015
62 цитирований
Voprosy pitaniia
2015
8 цитирований
The AAPS journal
2013
1866 цитирований
Molecular nutrition & …
2013
395 цитирований
Voprosy pitaniia
2013
Clinics (Sao Paulo, …
2010
47 цитирований
Indian journal of …
2010
14 цитирований
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 500-1,500 mg/day with piperine (black pepper extract) for absorption
- ibssupport:
- 500-1,000 mg/day
- ucmaintenance:
- 2,000 mg/day (1 g twice daily) as adjunct to mesalamine
Верхний предел: Well-tolerated up to 8 g/day in clinical trials (most studies use 1-2 g/day)
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | 1123 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| Peppermint oil, STW-5, psyllium, others | -- | Positive | -- |
| 200 mg | 8 weeks | Positive | -- |
Лучшее время приёма: With meals containing fat and black pepper for enhanced absorption
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ GI discomfort (nausea, diarrhea, abdominal pain) at high doses
- ⚠ Yellow staining of skin/teeth with topical/oral contact
- ⚠ Increased gallbladder contractions (avoid with gallstones or bile duct obstruction)
- ⚠ Iron chelation (may reduce iron absorption at very high doses)
Известные взаимодействия
- ● Anticoagulants (curcumin has antiplatelet properties; may increase bleeding risk)
- ● Chemotherapy agents (curcumin may alter drug metabolism via CYP enzyme inhibition)
- ● Sulfasalazine (additive anti-inflammatory effect — may be beneficial in IBD)
- ● Iron supplements (curcumin may chelate iron; space dosing)
- ● Piperine/black pepper (enhances curcumin bioavailability by 2,000% — commonly co-administered)
Допустимый верхний уровень потребления: Well-tolerated up to 8 g/day in clinical trials (most studies use 1-2 g/day)
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Curcumin help with Irritable Bowel Syndrome (IBS)?
Based on 2 studies with 200 participants, there is limited but promising evidence that Curcumin may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Curcumin should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 500-1,500 mg/day with piperine (black pepper extract) for absorption. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Curcumin?
Reported side effects may include GI discomfort (nausea, diarrhea, abdominal pain) at high doses, Yellow staining of skin/teeth with topical/oral contact, Increased gallbladder contractions (avoid with gallstones or bile duct obstruction), Iron chelation (may reduce iron absorption at very high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Curcumin and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 2 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
Related Evidence
Другие ингредиенты для Irritable Bowel Syndrome (IBS)
Curcumin для других состояний
References
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