알로에 베라(내엽 젤) 관련 과민성 대장 증후군(IBS)
C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.소규모 RCT에서 IBS 증상의 완만한 개선을 보였습니다. 결과가 혼재되어 있으며 일부 연구는 위약 대비 유익이 없었습니다.
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C
결론
소규모 RCT에서 IBS 증상의 완만한 개선을 보였습니다. 결과가 혼재되어 있으며 일부 연구는 위약 대비 유익이 없었습니다.
Key Study Findings
Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)
Review
Natural Products for the Treatment of Irritable Bowel Syndrome.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Patients with irritable bowel syndrome
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
vs: Various
Outcome: IBS symptom improvement
효과: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
대상 집단: Adult IBS patients
Controlled Clinical Trial
n=43
4 weeks
Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with …
Dose: 5 g/d
vs: None
Outcome: None
효과: None
None
대상 집단: IBS patients
Randomized Controlled Trial
n=160
Double-blind
Food supplements and diet as treatment options in irritable bowel syndrome.
Dose: None
vs: Placebo
Outcome: None
효과: None
None
대상 집단: IBS patients
Meta-Analysis
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Dose: None
vs: Placebo
Outcome: efficacy of Western herbal medicines in the treatment …
효과: None
None
대상 집단: IBS patients
Key Statistics
3
연구
250
참여자
↔
Mixed
C
등급
Referenced Papers
Nutrients
2026
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
Nutrition reviews
2025
10 인용
Gastroenterology & hepatology
2025
Nutrition research (New …
2020
42 인용
Neurogastroenterology and motility
2020
34 인용
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Meta-Analysis
Complementary therapies in …
2020
34 인용
Nutrients
2019
26 인용
Nutrients
2018
54 인용
Journal of neurogastroenterology …
2018
33 인용
Journal of gastrointestinal …
2015
36 인용
Journal of research …
2013
Chinese journal of …
2012
30 인용
ISRN gastroenterology
2011
30 인용
International journal of …
2006
50 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule
- ibssupport:
- 100 mL twice daily for 1-3 months
- constipation:
- 100-300 mg aloe latex (short-term only, maximum 1-2 weeks)
상한량: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| 5 g/d | 4 weeks | Positive | 43 |
| None | -- | Positive | 160 |
| None | -- | Positive | -- |
| 500 mg | 2.0 weeks | Positive | -- |
| None | -- | Mixed | -- |
권장 복용 시간: Before meals; aloe latex should only be used short-term for constipation
Safety & Side Effects
보고된 부작용
- ⚠ Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products)
- ⚠ Electrolyte imbalance (hypokalemia) with chronic laxative use
- ⚠ Potential hepatotoxicity with long-term whole leaf consumption (rare)
- ⚠ Allergic skin reactions in sensitive individuals
알려진 상호작용
- ● Digoxin (hypokalemia from laxative use may increase digoxin toxicity)
- ● Diuretics (additive potassium loss with aloe latex)
- ● Diabetes medications (aloe may lower blood sugar; monitor glucose)
- ● Stimulant laxatives (additive laxative effect; avoid combining)
- ● Anticoagulants (theoretical interaction due to platelet effects)
일일 최대 섭취 허용량: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 알로에 베라(내엽 젤) help with 과민성 대장 증후군(IBS)?
Based on 3 studies with 250 participants, there is limited but promising evidence that 알로에 베라(내엽 젤) may support 과민성 대장 증후군(IBS) management. Our evidence grade is C (Some Evidence).
How much 알로에 베라(내엽 젤) should I take for 과민성 대장 증후군(IBS)?
Studies have used various dosages. A commonly studied range is 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 알로에 베라(내엽 젤)?
Reported side effects may include Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products), Electrolyte imbalance (hypokalemia) with chronic laxative use, Potential hepatotoxicity with long-term whole leaf consumption (rare), Allergic skin reactions in sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 알로에 베라(내엽 젤) and 과민성 대장 증후군(IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 250 total participants. The overall direction of effect is mixed.
Related Evidence
관련 다른 성분: 과민성 대장 증후군(IBS)
알로에 베라(내엽 젤) 다른 건강 상태에 대한 근거
References
- [1] Ploutarchos Pastras et al.. Nutrients. 2026. Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines. doi:10.3390/nu18020183 PubMed
- [2] Sheida Zeraattalab-Motlagh et al.. Nutr Rev. 2025. Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical … doi:10.1093/nutrit/nuae107 PubMed
- [3] Sophie Brigstocke et al.. Gastroenterol Hepatol (N Y). 2025. Natural Products for the Treatment of Irritable Bowel Syndrome. PubMed
- [4] Karin Ried et al.. Nutr Res. 2020. Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders. doi:10.1016/j.nutres.2020.02.008 PubMed
- [5] Eirini Dimidi et al.. Neurogastroenterol Motil. 2020. Food supplements and diet as treatment options in irritable bowel syndrome. doi:10.1111/nmo.13951 PubMed
- [6] Jason A Hawrelak et al.. Complement Ther Med. 2020. Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis. doi:10.1016/j.ctim.2019.102233 PubMed
- [7] Carmen Parisio et al.. Nutrients. 2019. Researching New Therapeutic Approaches for Abdominal Visceral Pain Treatment: Preclinical Effects of an Assembled System of Molecules of Vegetal Origin. doi:10.3390/nu12010022 PubMed
- [8] Amanda C Fifi et al.. Nutrients. 2018. Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials. doi:10.3390/nu10111715 PubMed
- [9] Seung Wook Hong et al.. J Neurogastroenterol Motil. 2018. Aloe vera Is Effective and Safe in Short-term Treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-analysis. doi:10.5056/jnm18077 PubMed
- [10] Stine Størsrud et al.. J Gastrointestin Liver Dis. 2015. A Pilot Study of the Effect of Aloe barbadensis Mill. Extract (AVH200®) in Patients with Irritable Bowel Syndrome: a Randomized, … doi:10.15403/jgld.2014.1121.243.sst PubMed
- [11] Hossein Khedmat et al.. J Res Med Sci. 2013. Aloe vera in treatment of refractory irritable bowel syndrome: Trial on Iranian patients. PubMed
- [12] Azar Asadi-Shahmirzadi et al.. Chin J Integr Med. 2012. Benefit of Aloe vera and Matricaria recutita mixture in rat irritable bowel syndrome: Combination of antioxidant and spasmolytic effects. doi:10.1007/s11655-012-1027-9 PubMed
- [13] H A Hutchings et al.. ISRN Gastroenterol. 2011. A Randomised, Cross-Over, Placebo-Controlled Study of Aloe vera in Patients with Irritable Bowel Syndrome: Effects on Patient Quality of Life. doi:10.5402/2011/206103 PubMed
- [14] K Davis et al.. Int J Clin Pract. 2006. Randomised double-blind placebo-controlled trial of aloe vera for irritable bowel syndrome. doi:10.1111/j.1742-1241.2006.00980.x PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.