Aloe Vera (Inner Leaf Gel) 用于 Irritable Bowel Syndrome (IBS)
CSmall RCTs show modest improvement in IBS symptoms. Conflicting results; some studies show no benefit over placebo.
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C
结论
Small RCTs show modest improvement in IBS symptoms. Conflicting results; some studies show no benefit over placebo.
Key Study Findings
Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)
Review
Natural Products for the Treatment of Irritable Bowel Syndrome.
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: Patients with irritable bowel syndrome
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
vs: Various
Outcome: IBS symptom improvement
效果: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
研究人群: Adult IBS patients
Controlled Clinical Trial
n=43
4 weeks
Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with …
Dose: 5 g/d
vs: None
Outcome: None
效果: None
None
研究人群: IBS patients
Randomized Controlled Trial
n=160
Double-blind
Food supplements and diet as treatment options in irritable bowel syndrome.
Dose: None
vs: Placebo
Outcome: None
效果: None
None
研究人群: IBS patients
Meta-Analysis
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Dose: None
vs: Placebo
Outcome: efficacy of Western herbal medicines in the treatment …
效果: None
None
研究人群: IBS patients
Key Statistics
3
研究数量
250
受试者
↔
Mixed
C
等级
Referenced Papers
Nutrients
2026
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
Nutrition reviews
2025
10 次引用
Gastroenterology & hepatology
2025
Nutrition research (New …
2020
42 次引用
Neurogastroenterology and motility
2020
34 次引用
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Meta-Analysis
Complementary therapies in …
2020
34 次引用
Nutrients
2019
26 次引用
Nutrients
2018
54 次引用
Journal of neurogastroenterology …
2018
33 次引用
Journal of gastrointestinal …
2015
36 次引用
Journal of research …
2013
Chinese journal of …
2012
30 次引用
ISRN gastroenterology
2011
30 次引用
International journal of …
2006
50 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule
- ibssupport:
- 100 mL twice daily for 1-3 months
- constipation:
- 100-300 mg aloe latex (short-term only, maximum 1-2 weeks)
上限： No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| 5 g/d | 4 weeks | Positive | 43 |
| None | -- | Positive | 160 |
| None | -- | Positive | -- |
| 500 mg | 2.0 weeks | Positive | -- |
| None | -- | Mixed | -- |
最佳服用时间： Before meals; aloe latex should only be used short-term for constipation
Safety & Side Effects
已报告的副作用
- ⚠ Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products)
- ⚠ Electrolyte imbalance (hypokalemia) with chronic laxative use
- ⚠ Potential hepatotoxicity with long-term whole leaf consumption (rare)
- ⚠ Allergic skin reactions in sensitive individuals
已知相互作用
- ● Digoxin (hypokalemia from laxative use may increase digoxin toxicity)
- ● Diuretics (additive potassium loss with aloe latex)
- ● Diabetes medications (aloe may lower blood sugar; monitor glucose)
- ● Stimulant laxatives (additive laxative effect; avoid combining)
- ● Anticoagulants (theoretical interaction due to platelet effects)
可耐受最高摄入量： No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Aloe Vera (Inner Leaf Gel) help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 250 participants, there is limited but promising evidence that Aloe Vera (Inner Leaf Gel) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Aloe Vera (Inner Leaf Gel) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Aloe Vera (Inner Leaf Gel)?
Reported side effects may include Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products), Electrolyte imbalance (hypokalemia) with chronic laxative use, Potential hepatotoxicity with long-term whole leaf consumption (rare), Allergic skin reactions in sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Aloe Vera (Inner Leaf Gel) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 250 total participants. The overall direction of effect is mixed.
Related Evidence
其他成分用于 Irritable Bowel Syndrome (IBS)
Aloe Vera (Inner Leaf Gel) 用于其他健康状况
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