Vitamin D 관련 Inflammatory Bowel Disease (IBD) — General
BSupplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.
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B
결론
Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.
Key Study Findings
Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None
vs: None
Outcome: IBS symptom improvement with vitamin D supplementation
효과: None
None
대상 집단: individuals with irritable bowel syndrome
Review
Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: patients with ulcerative colitis
Review
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: review of probiotics as therapeutic strategy for inflammatory bowel disease
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
효과: None
None
대상 집단: Children with inflammatory bowel disease (review)
Observational Study
n=193
The importance of vitamin D levels in patients with inflammatory bowel disease.
Dose: None
vs: Clinical activity groups and VD status groups
Outcome: Vitamin D levels and IBD activity markers
효과: None
0.009 (CD), 0.033 (UC), 0.032
대상 집단: Greek IBD patients (122 CD, 71 UC)
Review
Osteoporosis: A Review.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Adults with osteoporosis
Key Statistics
10
연구
1500
참여자
↑
Positive
B
등급
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CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites.
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Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what …
Systematic Review
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Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
상한량: 4,000 IU/day (100 mcg); higher doses under medical supervision only
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Negative | 193 |
| None | -- | Mixed | -- |
| None | 690 weeks | Neutral | 357656 |
| None | -- | Positive | 310 |
권장 복용 시간: With a meal containing fat for better absorption
Safety & Side Effects
보고된 부작용
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
알려진 상호작용
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
일일 최대 섭취 허용량: 4,000 IU/day (100 mcg); higher doses under medical supervision only
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Vitamin D help with Inflammatory Bowel Disease (IBD) — General?
Based on 10 studies with 1,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Inflammatory Bowel Disease (IBD) — General management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Inflammatory Bowel Disease (IBD) — General?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Inflammatory Bowel Disease (IBD) — General?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: Inflammatory Bowel Disease (IBD) — General
Vitamin D 다른 건강 상태에 대한 근거
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.