Vitamin D untuk Inflammatory Bowel Disease (IBD) — General
BSupplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.
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B
Kesimpulan
Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.
Key Study Findings
Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None
vs: None
Outcome: IBS symptom improvement with vitamin D supplementation
Efek: None
None
Populasi: individuals with irritable bowel syndrome
Review
Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: patients with ulcerative colitis
Review
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: review of probiotics as therapeutic strategy for inflammatory bowel disease
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
Efek: None
None
Populasi: Children with inflammatory bowel disease (review)
Observational Study
n=193
The importance of vitamin D levels in patients with inflammatory bowel disease.
Dose: None
vs: Clinical activity groups and VD status groups
Outcome: Vitamin D levels and IBD activity markers
Efek: None
0.009 (CD), 0.033 (UC), 0.032
Populasi: Greek IBD patients (122 CD, 71 UC)
Review
Osteoporosis: A Review.
Dose: None
vs: None
Outcome: None
Efek: None
None
Populasi: Adults with osteoporosis
Key Statistics
10
Studi
1500
Peserta
↑
Positive
B
Peringkat
Referenced Papers
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2025
CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites.
Other
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Osteoporosis: A Review.
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JAMA
2025
Nutrients
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Vitamin D therapy in pediatric patients with inflammatory bowel disease: a systematic review and meta-analysis.
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Systematic Review
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Effects of oral vitamin D supplementation on inflammatory bowel disease: a systematic review and meta-analysis.
Meta-Analysis
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2021
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Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.
Systematic Review
Nutrients
2021
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Vitamin D Therapy in Adults With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
Meta-Analysis
Inflammatory bowel diseases
2020
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2020
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2020
10 sitasi
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2020
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Critical reviews in …
2019
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2019
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2019
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2019
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Current opinion in …
2018
94 sitasi
Gastroenterology clinics of …
2018
67 sitasi
Journal of research …
2018
48 sitasi
Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what …
Systematic Review
European journal of …
2018
39 sitasi
Gastroenterology
2017
335 sitasi
Fat-soluble Vitamin Deficiencies and Inflammatory Bowel Disease: Systematic Review and Meta-Analysis.
Meta-Analysis
Journal of clinical …
2017
73 sitasi
Nutrition in clinical …
2017
55 sitasi
PloS one
2017
38 sitasi
Control of Inflammatory Bowel Disease and Colorectal Cancer by Synthetic Vitamin D Receptor Ligands.
Review
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2017
14 sitasi
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2017
8 sitasi
Ugeskrift for laeger
2017
World journal of …
2016
238 sitasi
World journal of …
2016
122 sitasi
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Review
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2016
41 sitasi
Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn's Disease and Ulcerative Colitis.
Review
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2016
32 sitasi
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2016
22 sitasi
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2016
17 sitasi
Gastroenterology & hepatology
2016
7 sitasi
Association Between Inflammatory Bowel Disease and Vitamin D Deficiency: A Systematic Review and Meta-analysis.
Meta-Analysis
Inflammatory bowel diseases
2015
214 sitasi
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2015
149 sitasi
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2015
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2015
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2015
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2014
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2014
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2014
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2014
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2012
224 sitasi
Alimentary pharmacology & …
2012
111 sitasi
Current drug metabolism
2012
28 sitasi
Vitamins and hormones
2011
25 sitasi
Current opinion in …
2011
23 sitasi
Vitamin D and inflammation.
Review
Joint bone spine
2010
281 sitasi
Acta medica Indonesiana
2007
4 sitasi
Nature clinical practice. …
2005
191 sitasi
Alimentary pharmacology & …
2003
179 sitasi
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosis yang Umum Digunakan
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
Batas atas: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Dosis yang Diteliti dalam Penelitian
| Dosis | Durasi | Efek | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Negative | 193 |
| None | -- | Mixed | -- |
| None | 690 weeks | Neutral | 357656 |
| None | -- | Positive | 310 |
Waktu terbaik diminum: With a meal containing fat for better absorption
Safety & Side Effects
Efek Samping yang Dilaporkan
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
Interaksi yang Diketahui
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
Asupan atas yang dapat ditoleransi: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
Frequently Asked Questions
Does Vitamin D help with Inflammatory Bowel Disease (IBD) — General?
Based on 10 studies with 1,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Inflammatory Bowel Disease (IBD) — General management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Inflammatory Bowel Disease (IBD) — General?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Inflammatory Bowel Disease (IBD) — General?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.
Related Evidence
Bahan lain untuk Inflammatory Bowel Disease (IBD) — General
Vitamin D untuk kondisi lain
Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.