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Vitamin D pour Inflammatory Bowel Disease (IBD) — General

B Preuves Au moins un essai randomisé le soutient, avec des résultats globalement concordants.

Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.

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B

En conclusion

Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.

Key Study Findings

Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None vs: None Outcome: IBS symptom improvement with vitamin D supplementation Effet: None None

Population: individuals with irritable bowel syndrome

Review
Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.
Dose: None vs: None Outcome: None Effet: None None

Population: patients with ulcerative colitis

Review
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.
Dose: None vs: None Outcome: None Effet: None None

Population: review of probiotics as therapeutic strategy for inflammatory bowel disease

Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None vs: None Outcome: Micronutrient deficiency management in pediatric IBD Effet: None None

Population: Children with inflammatory bowel disease (review)

Observational Study n=193
The importance of vitamin D levels in patients with inflammatory bowel disease.
Dose: None vs: Clinical activity groups and VD status groups Outcome: Vitamin D levels and IBD activity markers Effet: None 0.009 (CD), 0.033 (UC), 0.032

Population: Greek IBD patients (122 CD, 71 UC)

Review
Osteoporosis: A Review.
Dose: None vs: None Outcome: None Effet: None None

Population: Adults with osteoporosis

Key Statistics

10

Études

1500

Participants

↑

Positive

B

Note

Referenced Papers

JAMA 2025
Swiss medical weekly 2024 9 citations
Nutricion hospitalaria 2024 2 citations
Paediatrics and international … 2023 48 citations
Archives of Iranian … 2023 2 citations
The Cochrane database … 2023 1 citations
Endocrine connections 2022 50 citations
Journal of inflammation … 2022 50 citations
Autoimmunity reviews 2022 44 citations
Frontiers in bioscience … 2022 17 citations
European journal of … 2021 40 citations
Autoimmunity reviews 2020 48 citations
Acta biochimica Polonica 2020 10 citations
The Korean journal … 2020 3 citations
Revista espanola de … 2020 2 citations
Frontline gastroenterology 2019 58 citations
Critical reviews in … 2019 45 citations
Complementary therapies in … 2019 27 citations
Current opinion in … 2019 5 citations
Current opinion in … 2018 94 citations
Gastroenterology clinics of … 2018 67 citations
Journal of research … 2018 48 citations
Gastroenterology 2017 335 citations
Nutrition in clinical … 2017 55 citations
World journal of … 2016 238 citations
Current gastroenterology reports 2016 22 citations
Journal of medicinal … 2016 17 citations
Gastroenterology & hepatology 2016 7 citations
BioMed research international 2015 149 citations
World journal of … 2015 62 citations
Healthcare (Basel, Switzerland) 2015 7 citations
Journal of inflammation … 2014 411 citations
Experimental biology and … 2014 131 citations
Inflammatory bowel diseases 2012 224 citations
Vitamins and hormones 2011 25 citations
Current opinion in … 2011 23 citations
Joint bone spine 2010 281 citations
Acta medica Indonesiana 2007 4 citations
Nature clinical practice. … 2005 191 citations
Alimentary pharmacology & … 2003 179 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
600-800 IU/day (RDA)
ibdsupport:
1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
deficiencycorrection:
50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance

Limite supérieure : 4,000 IU/day (100 mcg); higher doses under medical supervision only

Posologies étudiées dans la recherche

Posologie Durée Effet N
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Neutral --
None -- Negative 193
None -- Mixed --
None 690 weeks Neutral 357656
None -- Positive 310

Moment optimal de prise : With a meal containing fat for better absorption

Safety & Side Effects

Effets indésirables signalés

  • ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
  • ⚠ Kidney stones with excessive long-term supplementation
  • ⚠ Constipation
  • ⚠ Metallic taste

Interactions connues

  • ● Thiazide diuretics (may increase risk of hypercalcemia)
  • ● Corticosteroids (reduce vitamin D absorption and metabolism)
  • ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • ● Statins (vitamin D may affect statin metabolism)

Apport maximal tolérable : 4,000 IU/day (100 mcg); higher doses under medical supervision only

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Vitamin D help with Inflammatory Bowel Disease (IBD) — General?
Based on 10 studies with 1,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Inflammatory Bowel Disease (IBD) — General management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Inflammatory Bowel Disease (IBD) — General?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Inflammatory Bowel Disease (IBD) — General?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.

Autres ingrédients pour Inflammatory Bowel Disease (IBD) — General

Vitamin D pour d'autres pathologies

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