Vitamin D per Inflammatory Bowel Disease (IBD) — General
BSupplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'gutcited.com';
const params = 'ingredient\u003Dvitamin\u002Dd\u0026condition\u003Dinflammatory\u002Dbowel\u002Ddisease';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
B
In sintesi
Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.
Key Study Findings
Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None
vs: None
Outcome: IBS symptom improvement with vitamin D supplementation
Effetto: None
None
Popolazione: individuals with irritable bowel syndrome
Review
Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.
Dose: None
vs: None
Outcome: None
Effetto: None
None
Popolazione: patients with ulcerative colitis
Review
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.
Dose: None
vs: None
Outcome: None
Effetto: None
None
Popolazione: review of probiotics as therapeutic strategy for inflammatory bowel disease
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
Effetto: None
None
Popolazione: Children with inflammatory bowel disease (review)
Observational Study
n=193
The importance of vitamin D levels in patients with inflammatory bowel disease.
Dose: None
vs: Clinical activity groups and VD status groups
Outcome: Vitamin D levels and IBD activity markers
Effetto: None
0.009 (CD), 0.033 (UC), 0.032
Popolazione: Greek IBD patients (122 CD, 71 UC)
Review
Osteoporosis: A Review.
Dose: None
vs: None
Outcome: None
Effetto: None
None
Popolazione: Adults with osteoporosis
Key Statistics
10
Studi
1500
Partecipanti
↑
Positive
B
Grado
Referenced Papers
Gastroenterology nursing : …
None
4 citazioni
Digestive diseases and …
2026
1 citazioni
Trends in molecular …
2025
35 citazioni
Arquivos de neuro-psiquiatria
2025
6 citazioni
Nutrients
2025
4 citazioni
Journal of physiology …
2025
3 citazioni
The American journal …
2025
CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites.
Other
Scientific reports
2025
Osteoporosis: A Review.
Review
JAMA
2025
Nutrients
2024
47 citazioni
Nutrients
2024
27 citazioni
Swiss medical weekly
2024
9 citazioni
Nutricion hospitalaria
2024
2 citazioni
Asia Pacific journal …
2024
1 citazioni
Paediatrics and international …
2023
48 citazioni
The American journal …
2023
37 citazioni
Vitamin D therapy in pediatric patients with inflammatory bowel disease: a systematic review and meta-analysis.
Meta-Analysis
World journal of …
2023
11 citazioni
Frontiers in pediatrics
2023
6 citazioni
JGH open : …
2023
5 citazioni
Toxicology mechanisms and …
2023
5 citazioni
Archives of Iranian …
2023
2 citazioni
Vitamin D for the treatment of inflammatory bowel disease.
Systematic Review
The Cochrane database …
2023
1 citazioni
Endocrine connections
2022
50 citazioni
Journal of inflammation …
2022
50 citazioni
Autoimmunity reviews
2022
44 citazioni
Frontiers in bioscience …
2022
17 citazioni
PloS one
2022
10 citazioni
Medwave
2022
4 citazioni
European journal of …
2021
40 citazioni
Effects of oral vitamin D supplementation on inflammatory bowel disease: a systematic review and meta-analysis.
Meta-Analysis
Food & function
2021
25 citazioni
Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.
Systematic Review
Nutrients
2021
16 citazioni
Vitamin D Therapy in Adults With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
Meta-Analysis
Inflammatory bowel diseases
2020
57 citazioni
Autoimmunity reviews
2020
48 citazioni
Acta biochimica Polonica
2020
10 citazioni
The Korean journal …
2020
3 citazioni
Revista espanola de …
2020
2 citazioni
Nutrients
2019
193 citazioni
Frontline gastroenterology
2019
58 citazioni
Critical reviews in …
2019
45 citazioni
Complementary therapies in …
2019
27 citazioni
Current drug metabolism
2019
7 citazioni
Current opinion in …
2019
5 citazioni
Current opinion in …
2018
94 citazioni
Gastroenterology clinics of …
2018
67 citazioni
Journal of research …
2018
48 citazioni
Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what …
Systematic Review
European journal of …
2018
39 citazioni
Gastroenterology
2017
335 citazioni
Fat-soluble Vitamin Deficiencies and Inflammatory Bowel Disease: Systematic Review and Meta-Analysis.
Meta-Analysis
Journal of clinical …
2017
73 citazioni
Nutrition in clinical …
2017
55 citazioni
PloS one
2017
38 citazioni
Control of Inflammatory Bowel Disease and Colorectal Cancer by Synthetic Vitamin D Receptor Ligands.
Review
Current medicinal chemistry
2017
14 citazioni
Clinical gastroenterology and …
2017
8 citazioni
Ugeskrift for laeger
2017
World journal of …
2016
238 citazioni
World journal of …
2016
122 citazioni
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Review
Digestive diseases (Basel, …
2016
41 citazioni
Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn's Disease and Ulcerative Colitis.
Review
Current pharmaceutical design
2016
32 citazioni
Current gastroenterology reports
2016
22 citazioni
Journal of medicinal …
2016
17 citazioni
Gastroenterology & hepatology
2016
7 citazioni
Association Between Inflammatory Bowel Disease and Vitamin D Deficiency: A Systematic Review and Meta-analysis.
Meta-Analysis
Inflammatory bowel diseases
2015
214 citazioni
BioMed research international
2015
149 citazioni
World journal of …
2015
62 citazioni
The Proceedings of …
2015
46 citazioni
Healthcare (Basel, Switzerland)
2015
7 citazioni
Journal of inflammation …
2014
411 citazioni
Experimental biology and …
2014
131 citazioni
World journal of …
2014
117 citazioni
Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.
Other
Journal of pediatric …
2014
38 citazioni
Inflammatory bowel diseases
2012
224 citazioni
Alimentary pharmacology & …
2012
111 citazioni
Current drug metabolism
2012
28 citazioni
Vitamins and hormones
2011
25 citazioni
Current opinion in …
2011
23 citazioni
Vitamin D and inflammation.
Review
Joint bone spine
2010
281 citazioni
Acta medica Indonesiana
2007
4 citazioni
Nature clinical practice. …
2005
191 citazioni
Alimentary pharmacology & …
2003
179 citazioni
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosaggi di uso comune
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
Limite massimo: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Dosaggi studiati nella ricerca
| Dosaggio | Durata | Effetto | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Neutral | -- |
| None | -- | Negative | 193 |
| None | -- | Mixed | -- |
| None | 690 weeks | Neutral | 357656 |
| None | -- | Positive | 310 |
Momento migliore per l'assunzione: With a meal containing fat for better absorption
Safety & Side Effects
Effetti collaterali segnalati
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
Interazioni note
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
Livello di assunzione massimo tollerabile: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
Frequently Asked Questions
Does Vitamin D help with Inflammatory Bowel Disease (IBD) — General?
Based on 10 studies with 1,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Inflammatory Bowel Disease (IBD) — General management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Inflammatory Bowel Disease (IBD) — General?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Inflammatory Bowel Disease (IBD) — General?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.
Related Evidence
Altri ingredienti per Inflammatory Bowel Disease (IBD) — General
Vitamin D per altre condizioni
Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.