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Vitamin D لـ Inflammatory Bowel Disease (IBD) — General

B

Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.

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B

الخلاصة

Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.

Key Study Findings

Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None مقابل: None Outcome: IBS symptom improvement with vitamin D supplementation التأثير: None None

المجتمع المدروس: individuals with irritable bowel syndrome

Review
Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: patients with ulcerative colitis

Review
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: review of probiotics as therapeutic strategy for inflammatory bowel disease

Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None مقابل: None Outcome: Micronutrient deficiency management in pediatric IBD التأثير: None None

المجتمع المدروس: Children with inflammatory bowel disease (review)

Observational Study n=193
The importance of vitamin D levels in patients with inflammatory bowel disease.
Dose: None مقابل: Clinical activity groups and VD status groups Outcome: Vitamin D levels and IBD activity markers التأثير: None 0.009 (CD), 0.033 (UC), 0.032

المجتمع المدروس: Greek IBD patients (122 CD, 71 UC)

Review
Osteoporosis: A Review.
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: Adults with osteoporosis

Key Statistics

10

الدراسات

1500

المشاركون

Positive

B

التقييم

Referenced Papers

Journal of physiology … 2025 3 اقتباسات
JAMA 2025
Swiss medical weekly 2024 9 اقتباسات
Nutricion hospitalaria 2024 2 اقتباسات
Paediatrics and international … 2023 48 اقتباسات
JGH open : … 2023 5 اقتباسات
Archives of Iranian … 2023 2 اقتباسات
The Cochrane database … 2023 1 اقتباسات
Endocrine connections 2022 50 اقتباسات
Journal of inflammation … 2022 50 اقتباسات
Autoimmunity reviews 2022 44 اقتباسات
Frontiers in bioscience … 2022 17 اقتباسات
European journal of … 2021 40 اقتباسات
Autoimmunity reviews 2020 48 اقتباسات
Acta biochimica Polonica 2020 10 اقتباسات
The Korean journal … 2020 3 اقتباسات
Revista espanola de … 2020 2 اقتباسات
Frontline gastroenterology 2019 58 اقتباسات
Critical reviews in … 2019 45 اقتباسات
Complementary therapies in … 2019 27 اقتباسات
Current opinion in … 2019 5 اقتباسات
Current opinion in … 2018 94 اقتباسات
Gastroenterology clinics of … 2018 67 اقتباسات
Journal of research … 2018 48 اقتباسات
Gastroenterology 2017 335 اقتباسات
Nutrition in clinical … 2017 55 اقتباسات
PloS one 2017 38 اقتباسات
World journal of … 2016 238 اقتباسات
Current gastroenterology reports 2016 22 اقتباسات
Journal of medicinal … 2016 17 اقتباسات
Gastroenterology & hepatology 2016 7 اقتباسات
BioMed research international 2015 149 اقتباسات
World journal of … 2015 62 اقتباسات
Healthcare (Basel, Switzerland) 2015 7 اقتباسات
Journal of inflammation … 2014 411 اقتباسات
Experimental biology and … 2014 131 اقتباسات
Inflammatory bowel diseases 2012 224 اقتباسات
Current drug metabolism 2012 28 اقتباسات
Vitamins and hormones 2011 25 اقتباسات
Current opinion in … 2011 23 اقتباسات
Joint bone spine 2010 281 اقتباسات
Acta medica Indonesiana 2007 4 اقتباسات
Nature clinical practice. … 2005 191 اقتباسات
Alimentary pharmacology & … 2003 179 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
600-800 IU/day (RDA)
ibdsupport:
1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
deficiencycorrection:
50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance

الحد الأعلى: 4,000 IU/day (100 mcg); higher doses under medical supervision only

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Neutral --
None -- Negative 193
None -- Mixed --
None 690 weeks Neutral 357656
None -- Positive 310

أفضل وقت للتناول: With a meal containing fat for better absorption

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
  • Kidney stones with excessive long-term supplementation
  • Constipation
  • Metallic taste

التفاعلات المعروفة

  • Thiazide diuretics (may increase risk of hypercalcemia)
  • Corticosteroids (reduce vitamin D absorption and metabolism)
  • Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • Statins (vitamin D may affect statin metabolism)

الحد الأقصى المسموح به: 4,000 IU/day (100 mcg); higher doses under medical supervision only

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Vitamin D help with Inflammatory Bowel Disease (IBD) — General?
Based on 10 studies with 1,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Inflammatory Bowel Disease (IBD) — General management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Inflammatory Bowel Disease (IBD) — General?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Inflammatory Bowel Disease (IBD) — General?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.

Related Evidence

مكونات أخرى لـ Inflammatory Bowel Disease (IBD) — General

Vitamin D لحالات أخرى

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.