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Vitamin D para Inflammatory Bowel Disease (IBD) — General

B

Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.

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B

Conclusión

Supplementation (1,000-4,000 IU/day) reduces relapse risk in both UC and Crohn's. Deficiency is common in IBD (up to 60%) and correlates with disease severity.

Key Study Findings

Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None vs: None Outcome: IBS symptom improvement with vitamin D supplementation Efecto: None None

Población: individuals with irritable bowel syndrome

Review
Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.
Dose: None vs: None Outcome: None Efecto: None None

Población: patients with ulcerative colitis

Review
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.
Dose: None vs: None Outcome: None Efecto: None None

Población: review of probiotics as therapeutic strategy for inflammatory bowel disease

Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None vs: None Outcome: Micronutrient deficiency management in pediatric IBD Efecto: None None

Población: Children with inflammatory bowel disease (review)

Observational Study n=193
The importance of vitamin D levels in patients with inflammatory bowel disease.
Dose: None vs: Clinical activity groups and VD status groups Outcome: Vitamin D levels and IBD activity markers Efecto: None 0.009 (CD), 0.033 (UC), 0.032

Población: Greek IBD patients (122 CD, 71 UC)

Review
Osteoporosis: A Review.
Dose: None vs: None Outcome: None Efecto: None None

Población: Adults with osteoporosis

Key Statistics

10

Estudios

1500

Participantes

Positive

B

Calificación

Referenced Papers

JAMA 2025
Swiss medical weekly 2024 9 citas
Paediatrics and international … 2023 48 citas
Archives of Iranian … 2023 2 citas
The Cochrane database … 2023 1 citas
Endocrine connections 2022 50 citas
Journal of inflammation … 2022 50 citas
Frontiers in bioscience … 2022 17 citas
European journal of … 2021 40 citas
Autoimmunity reviews 2020 48 citas
Acta biochimica Polonica 2020 10 citas
The Korean journal … 2020 3 citas
Frontline gastroenterology 2019 58 citas
Critical reviews in … 2019 45 citas
Current opinion in … 2019 5 citas
Gastroenterology clinics of … 2018 67 citas
Journal of research … 2018 48 citas
Nutrition in clinical … 2017 55 citas
World journal of … 2016 238 citas
Current gastroenterology reports 2016 22 citas
Journal of medicinal … 2016 17 citas
Gastroenterology & hepatology 2016 7 citas
BioMed research international 2015 149 citas
World journal of … 2015 62 citas
Healthcare (Basel, Switzerland) 2015 7 citas
Journal of inflammation … 2014 411 citas
Inflammatory bowel diseases 2012 224 citas
Vitamins and hormones 2011 25 citas
Joint bone spine 2010 281 citas
Acta medica Indonesiana 2007 4 citas
Nature clinical practice. … 2005 191 citas
Alimentary pharmacology & … 2003 179 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:
600-800 IU/day (RDA)
ibdsupport:
1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
deficiencycorrection:
50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance

Límite superior: 4,000 IU/day (100 mcg); higher doses under medical supervision only

Dosificaciones estudiadas en la investigación

Dosificación Duración Efecto N
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Neutral --
None -- Negative 193
None -- Mixed --
None 690 weeks Neutral 357656
None -- Positive 310

Mejor momento para tomar: With a meal containing fat for better absorption

Safety & Side Effects

Efectos secundarios reportados

  • Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
  • Kidney stones with excessive long-term supplementation
  • Constipation
  • Metallic taste

Interacciones conocidas

  • Thiazide diuretics (may increase risk of hypercalcemia)
  • Corticosteroids (reduce vitamin D absorption and metabolism)
  • Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • Statins (vitamin D may affect statin metabolism)

Ingesta máxima tolerable: 4,000 IU/day (100 mcg); higher doses under medical supervision only

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Vitamin D help with Inflammatory Bowel Disease (IBD) — General?
Based on 10 studies with 1,500 participants, there is moderate evidence from clinical studies that Vitamin D may support Inflammatory Bowel Disease (IBD) — General management. Our evidence grade is B (Good Evidence).
How much Vitamin D should I take for Inflammatory Bowel Disease (IBD) — General?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Inflammatory Bowel Disease (IBD) — General?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 1,500 total participants. The overall direction of effect is positive.

Related Evidence

Otros ingredientes para Inflammatory Bowel Disease (IBD) — General

Vitamin D para otras condiciones

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.