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Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

I Sakamoto, M Igarashi, K Kimura, A Takagi, T Miwa et al.
Other The Journal of antimicrobial chemotherapy 2001 309 उद्धरण
PubMed DOI
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Study Design

अध्ययन प्रकार
Controlled Clinical Trial
नमूना आकार
31
जनसंख्या
H. pylori-infected subjects
अवधि
8 weeks
हस्तक्षेप
Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. LG21 yogurt daily for 8 weeks
तुलनित्र
Before-after comparison
प्राथमिक परिणाम
H. pylori suppression (UBT, pepsinogens)
प्रभाव की दिशा
Positive
पूर्वाग्रह का जोखिम
Moderate

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

संक्षेप में

LG21 was determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation and a significant improvement following LG21 treatment.

Used In Evidence Reviews

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