साक्ष्य-आधारित सप्लीमेंट समीक्षाएँ
Every gut claim cited.
We read the gut health studies so you don't have to.
Evidence-based supplement research you can trust. We analyze peer-reviewed clinical studies from PubMed and grade every supplement ingredient on a transparent A–D scale. No sponsored rankings, no manufacturer influence — just science.
Featured Ingredients
Zinc
mineralEssential cofactor for intestinal alkaline phosphatase detoxifying bacterial endotoxin (LPS); maintains tight junction integrity via claudin and occludin expression; supports …
Lactobacillus rhamnosus GG
probiotic_strainEnhances gut barrier function by upregulating tight junction proteins (claudin-1, occludin, ZO-1) and modulates intestinal immune response via Toll-like receptor …
Saccharomyces boulardii
probiotic_strainNon-pathogenic yeast that secretes a 54-kDa protease degrading C. difficile toxins A and B; enhances secretory IgA production protecting mucosal …
Lactobacillus acidophilus
probiotic_strainProduces lactic acid lowering intestinal pH to inhibit pathogen growth; inhibits pathogen adhesion to intestinal epithelium via competitive exclusion; enhances …
Lactobacillus plantarum
probiotic_strainAdheres strongly to intestinal mucosa competing with pathogens for binding sites; produces plantaricin antimicrobial peptides with broad-spectrum activity; modulates NF-kB …
Bifidobacterium longum
probiotic_strainFerments complex carbohydrates producing acetate and lactate that lower colonic pH; reduces visceral hypersensitivity via serotonin pathway modulation; downregulates pro-inflammatory …
Top Conditions
Gastroesophageal Reflux Disease (GERD)
20-30% in Western populations; 5-10% in Asia
Chronic Constipation
15-20% of adults globally; increases with age; more common in women
Acute Diarrhea
1.7 billion cases of childhood diarrhea globally per year; 525,000 deaths
Antibiotic-Associated Diarrhea (AAD)
5-39% of antibiotic users; varies by antibiotic class
Clostridioides difficile Infection (CDI)
500,000 infections/year in the US; 29,000 deaths
Ulcerative Colitis (UC)
~0.3% in Western countries; peak onset 15-30 years
Recent Evidence Updates
3 अध्ययन
4 अध्ययन
3 अध्ययन
3 अध्ययन
4 अध्ययन
Popular Comparisons
Latest Research
Front Immunol · 2019
Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases.
Am J Clin Nutr · 1991
Omega-3 fatty acids in health and disease and in growth and development.
J Am Coll Nutr · 2002
Omega-3 fatty acids in inflammation and autoimmune diseases.
AAPS J · 2013
Therapeutic roles of curcumin: lessons learned from clinical trials.
Proc Natl Acad Sci … · 2014
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition.
Gut · 2014
A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis.
Guides & Resources
Managing Stress-Related Gut Issues: The Mind-Body Connection in Digestive Health
The intimate connection between psychological stress and digestive symptoms is a common lived experience — the butterflies before a presentation, the loss of appetite during …
lifestyleDiet and Gut Health: Evidence-Based Nutritional Strategies for Digestive Wellness
Diet is widely recognized as one of the most powerful modulators of the gut microbiome, with research demonstrating that dietary changes can alter microbial composition …
safetyDigestive Enzyme Supplements: Types, Timing, and Safe Use
Digestive enzymes are proteins produced naturally by the body to break down food into absorbable nutrients. The major categories include proteases that break down proteins, …
Evidence Grading System
Every supplement claim on this site is graded on an A–D scale based on peer-reviewed clinical research from PubMed. Our algorithm evaluates study design (RCTs rank highest), consistency of results, sample sizes, and the overall body of evidence. No manufacturer sponsorship influences our grades.
Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.
At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.
Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.
In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.
How It Works
कोई विज्ञापन नहीं। कोई प्रायोजित रैंकिंग नहीं। केवल विज्ञान।
अनुसंधान हब
हम सप्लीमेंट सामग्री पर प्रत्येक नैदानिक अध्ययन के लिए PubMed खोजते हैं।
निष्कर्षण
हम प्रमुख निष्कर्ष निकालते हैं — नमूना आकार, अध्ययन के प्रकार और परिणाम।
A से F तक ग्रेडिंग
हम साक्ष्य को स्कूल रिपोर्ट कार्ड की तरह ग्रेड करते हैं — A (मजबूत) से F (नकारात्मक) तक।
स्पष्ट उत्तर
आपको सेकंडों में स्पष्ट उत्तर मिलता है — क्या यह सप्लीमेंट वास्तव में काम करता है?
Cited Health Network
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FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।