Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

I Sakamoto, M Igarashi, K Kimura, A Takagi, T Miwa et al.

Other The Journal of antimicrobial chemotherapy 2001 309 件の引用

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Study Design

研究タイプ: Controlled Clinical Trial
サンプルサイズ: 31
対象集団: H. pylori-infected subjects
期間: 8 weeks

介入: Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. LG21 yogurt daily for 8 weeks
比較対照: Before-after comparison
主要アウトカム: H. pylori suppression (UBT, pepsinogens)
効果の方向: Positive
バイアスリスク: Moderate

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

要約

LG21 was determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation and a significant improvement following LG21 treatment.

Used In Evidence Reviews

B Lactobacillus gasseri ： Helicobacter pylori Infection

D Lactobacillus gasseri ： Gastroesophageal Reflux Disease (GERD)

Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

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Study Design

Abstract

要約

Used In Evidence Reviews

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