Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

I Sakamoto, M Igarashi, K Kimura, A Takagi, T Miwa et al.

Other The Journal of antimicrobial chemotherapy 2001 309 اقتباسات

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Study Design

نوع الدراسة: Controlled Clinical Trial
حجم العينة: 31
المجتمع المدروس: H. pylori-infected subjects
المدة: 8 weeks

التدخل: Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. LG21 yogurt daily for 8 weeks
المقارن: Before-after comparison
النتيجة الأولية: H. pylori suppression (UBT, pepsinogens)
اتجاه التأثير: Positive
خطر التحيز: Moderate

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

باختصار

LG21 was determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation and a significant improvement following LG21 treatment.

Used In Evidence Reviews

B Lactobacillus gasseri لـ Helicobacter pylori Infection

D Lactobacillus gasseri لـ Gastroesophageal Reflux Disease (GERD)

Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

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Study Design

Abstract

باختصار

Used In Evidence Reviews

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