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Lactobacillus gasseri के लिए Gastroesophageal Reflux Disease (GERD)

D

Emerging evidence from Japanese studies. May reduce acid-related symptoms. Not yet replicated in Western populations.

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D

निष्कर्ष

Emerging evidence from Japanese studies. May reduce acid-related symptoms. Not yet replicated in Western populations.

Key Study Findings

Meta-Analysis
Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome.
Dose: None बनाम: placebo Outcome: improvement in key IBS symptoms प्रभाव: None None

जनसंख्या: patients with IBS from 32 RCTs evaluating 10 probiotic strains

In Vitro
Lactobacillus gasseri suppresses the Helicobacter pylori-induced expression of the proliferation-associated factors HBEGF and TGF-α in …
Dose: None बनाम: H. pylori infection without lactobacilli Outcome: ADAM17, HBEGF, TGF-alpha expression प्रभाव: None None

जनसंख्या: AGS gastric epithelial cells and mouse model

In Vitro
The modulatory effect of Lactobacillus gasseri ATCC 33323 on autophagy induced by extracellular vesicles of …
Dose: 50 μg/ml बनाम: None Outcome: Inflammatory markers प्रभाव: None None

जनसंख्या: None

Other
Effect of Lactobacillus gasseri BIO6369 and Lacticaseibacillus rhamnosus BIO5326 on Gastric Carcinogenesis Induced by Helicobacter …
Dose: None बनाम: None Outcome: Inflammatory markers प्रभाव: None None

जनसंख्या: Cancer patients

In Vitro
Effects of Glutamine, Curcumin and Fish Bioactive Peptides Alone or in Combination on Intestinal Permeability …
Dose: None बनाम: None Outcome: inflammation markers प्रभाव: None None

जनसंख्या: Mice

Case-Control n=178
Oral and gastric microbiome in relation to gastric intestinal metaplasia.
Dose: None बनाम: None Outcome: Oral/gastric microbiome associations with IM प्रभाव: None None

जनसंख्या: Gastric intestinal metaplasia cases and matched controls

Key Statistics

3

अध्ययन

300

प्रतिभागी

Positive

D

ग्रेड

Referenced Papers

International journal of … 2022 59 उद्धरण
Comparative immunology, microbiology … 2019 72 उद्धरण
Probiotics and antimicrobial … 2010 9 उद्धरण

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

general:
1-10 billion CFU/day
gerdsupport:
1-5 billion CFU/day
hpylorisupport:
100 million CFU/day (LG21 strain, yogurt form) for 8-12 weeks

अधिकतम सीमा: Well-tolerated up to 10 billion CFU/day in clinical trials

अनुसंधान में अध्ययन की गई खुराकें

खुराक अवधि प्रभाव N
None -- Positive --
None -- Positive --
50 μg/ml -- Mixed --
None -- Positive --
None -- Mixed --
None -- Neutral 178
None -- Positive --
None -- Positive --

सेवन का सर्वोत्तम समय: Before meals or with meals; yogurt form taken with food

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

  • Mild gas during initial use
  • Occasional loose stools
  • Rare abdominal discomfort
  • Very rare: bacteremia in immunocompromised individuals

ज्ञात अंतःक्रियाएँ

  • Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
  • Proton pump inhibitors (altered gastric pH may affect colonization)
  • Immunosuppressants (theoretical risk in immunocompromised patients)

सहनीय अधिकतम सेवन: Well-tolerated up to 10 billion CFU/day in clinical trials

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Lactobacillus gasseri help with Gastroesophageal Reflux Disease (GERD)?
Based on 3 studies with 300 participants, there is preliminary evidence that needs more research that Lactobacillus gasseri may support Gastroesophageal Reflux Disease (GERD) management. Our evidence grade is D (Very Early Research).
How much Lactobacillus gasseri should I take for Gastroesophageal Reflux Disease (GERD)?
Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lactobacillus gasseri?
Reported side effects may include Mild gas during initial use, Occasional loose stools, Rare abdominal discomfort, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lactobacillus gasseri and Gastroesophageal Reflux Disease (GERD)?
We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.

Related Evidence

इसके लिए अन्य सामग्री Gastroesophageal Reflux Disease (GERD)

Lactobacillus gasseri अन्य स्वास्थ्य स्थितियों के लिए

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।