Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

I Sakamoto, M Igarashi, K Kimura, A Takagi, T Miwa et al.

Other The Journal of antimicrobial chemotherapy 2001 309 atıf

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Study Design

Çalışma Türü: Controlled Clinical Trial
Örneklem Büyüklüğü: 31
Popülasyon: H. pylori-infected subjects
Süre: 8 weeks

Müdahale: Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. LG21 yogurt daily for 8 weeks
Karşılaştırıcı: Before-after comparison
Birincil Sonuç: H. pylori suppression (UBT, pepsinogens)
Etki Yönü: Positive
Yanlılık Riski: Moderate

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

Kısaca

LG21 was determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation and a significant improvement following LG21 treatment.

Used In Evidence Reviews

B Lactobacillus gasseri için Helicobacter pylori Infection

D Lactobacillus gasseri için Gastroesophageal Reflux Disease (GERD)

Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

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Study Design

Abstract

Kısaca

Used In Evidence Reviews

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