Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

I Sakamoto, M Igarashi, K Kimura, A Takagi, T Miwa et al.

Other The Journal of antimicrobial chemotherapy 2001 309 цитирований

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Study Design

Тип исследования: Controlled Clinical Trial
Размер выборки: 31
Популяция: H. pylori-infected subjects
Длительность: 8 weeks

Вмешательство: Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. LG21 yogurt daily for 8 weeks
Препарат сравнения: Before-after comparison
Первичный исход: H. pylori suppression (UBT, pepsinogens)
Направление эффекта: Positive
Риск систематической ошибки: Moderate

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

Кратко

LG21 was determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation and a significant improvement following LG21 treatment.

Used In Evidence Reviews

B Lactobacillus gasseri для Helicobacter pylori Infection

D Lactobacillus gasseri для Gastroesophageal Reflux Disease (GERD)

Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

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Study Design

Abstract

Кратко

Used In Evidence Reviews

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