Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

I Sakamoto, M Igarashi, K Kimura, A Takagi, T Miwa et al.

Other The Journal of antimicrobial chemotherapy 2001 309 citações

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Study Design

Tipo de Estudo: Controlled Clinical Trial
Tamanho da Amostra: 31
População: H. pylori-infected subjects
Duração: 8 weeks

Intervenção: Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. LG21 yogurt daily for 8 weeks
Comparador: Before-after comparison
Desfecho Primário: H. pylori suppression (UBT, pepsinogens)
Direção do Efeito: Positive
Risco de Viés: Moderate

Abstract

To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.

Resumo Rápido

LG21 was determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation and a significant improvement following LG21 treatment.

Used In Evidence Reviews

B Lactobacillus gasseri para Helicobacter pylori Infection

D Lactobacillus gasseri para Gastroesophageal Reflux Disease (GERD)

Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.

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Study Design

Abstract

Resumo Rápido

Used In Evidence Reviews

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