Partially Hydrolyzed Guar Gum (PHGG) के लिए Irritable Bowel Syndrome (IBS)
B संबंधित साक्ष्य कम से कम एक यादृच्छिक परीक्षण इसका समर्थन करता है, जिसके परिणाम अधिकतर सुसंगत हैं।Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.
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B
निष्कर्ष
Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.
Key Study Findings
Randomized Controlled Trial
n=47
8 weeks
Double-blind
Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and …
Dose: None
बनाम: Placebo (Group I) and partial formulation (Group II)
Outcome: IBS quality of life (QoL questionnaire)
प्रभाव: Dysphoria: median diff -5 (Group III) vs -1 (contr
0.0021 (dysphoria Group III)
जनसंख्या: Patients with IBS
Controlled Clinical Trial
Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable …
Dose: Partially hydrolyzed guar gum (PHGG)
बनाम: Drug therapy alone
Outcome: Gut bacteria ratios and inflammatory markers
प्रभाव: None
None
जनसंख्या: Patients with IBD or IBS on drug therapy
Controlled Clinical Trial
12.9 weeks
Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel …
Dose: None
बनाम: baseline
Outcome: IBS symptom improvement
प्रभाव: None
None
जनसंख्या: Ibs undertook a 90-day intervention and follow-up
Case Reports
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: None
Randomized Controlled Trial
13.0 weeks
Double-blind
Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: …
Dose: None
बनाम: Placebo
Outcome: Bowel function
प्रभाव: None
p=0.05
जनसंख्या: healthy volunteers
Randomized Controlled Trial
12 weeks
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients …
Dose: partially hydrolyzed guar gum (PHGG) 5g/day
बनाम: placebo
Outcome: IBS-SSS and bloating severity
प्रभाव: significant improvement in overall IBS-SSS
<0.05
जनसंख्या: Adults with IBS
Key Statistics
5
अध्ययन
350
प्रतिभागी
↑
Positive
B
ग्रेड
Referenced Papers
Frontiers in nutrition
2025
3 उद्धरण
The journal of …
2024
2 उद्धरण
Nutrients
2023
3 उद्धरण
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Case Report
Expert review of …
2021
7 उद्धरण
Nutrients
2019
68 उद्धरण
Nutrition & metabolism
2016
61 उद्धरण
Probiotics for Irritable Bowel Syndrome: Clinical Data in Children.
Systematic Review
Journal of pediatric …
2016
19 उद्धरण
Saudi journal of …
2015
32 उद्धरण
World journal of …
2013
69 उद्धरण
Minerva gastroenterologica e …
2013
Nutrition (Burbank, Los …
2006
119 उद्धरण
Digestive diseases and …
2005
55 उद्धरण
Nutrition (Burbank, Los …
2003
143 उद्धरण
Digestive diseases and …
2002
117 उद्धरण
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- general:
- 5-7 g/day
- ibssupport:
- 5 g/day for 4-12 weeks
- siboadjunct:
- 5 g/day alongside antimicrobial therapy
अधिकतम सीमा: Well-tolerated up to 36 g/day in clinical trials
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | 8 weeks | Positive | 47 |
| Partially hydrolyzed guar gum (PHGG) | -- | Positive | -- |
| None | 12.9 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | 13.0 weeks | Mixed | -- |
| partially hydrolyzed guar gum (PHGG) 5g/day | 12 weeks | Positive | -- |
| various probiotic strains | -- | Mixed | -- |
| None | 4.0 weeks | Positive | -- |
सेवन का सर्वोत्तम समय: Mixed into food or beverages; dissolves completely without altering texture
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Minimal gas and bloating (significantly less than other fibers)
- ⚠ Mild abdominal discomfort in rare cases
- ⚠ Loose stools at very high doses
ज्ञात अंतःक्रियाएँ
- ● May slow absorption of some medications (space 1-2 hours)
- ● Diabetes medications (may modestly affect blood glucose)
सहनीय अधिकतम सेवन: Well-tolerated up to 36 g/day in clinical trials
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Partially Hydrolyzed Guar Gum (PHGG) help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 350 participants, there is moderate evidence from clinical studies that Partially Hydrolyzed Guar Gum (PHGG) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Partially Hydrolyzed Guar Gum (PHGG) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 5-7 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Partially Hydrolyzed Guar Gum (PHGG)?
Reported side effects may include Minimal gas and bloating (significantly less than other fibers), Mild abdominal discomfort in rare cases, Loose stools at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Partially Hydrolyzed Guar Gum (PHGG) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.
Related Evidence
इसके लिए अन्य सामग्री Irritable Bowel Syndrome (IBS)
Partially Hydrolyzed Guar Gum (PHGG) अन्य स्वास्थ्य स्थितियों के लिए
References
- [1] Adrianna Wierzbicka et al.. Front Nutr. 2025. Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients … doi:10.3389/fnut.2025.1603011 PubMed
- [2] Hideo Watanabe et al.. J Med Invest. 2024. Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable bowel syndrome induced by the … doi:10.2152/jmi.71.121 PubMed
- [3] Jerry Zhou et al.. Nutrients. 2023. Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel Syndrome. doi:10.3390/nu15224786 PubMed
- [4] Claudio Romano et al.. Expert Rev Gastroenterol Hepatol. 2021. Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases. doi:10.1080/17474124.2021.1884543 PubMed
- [5] Zenta Yasukawa et al.. Nutrients. 2019. Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled, and … doi:10.3390/nu11092170 PubMed
- [6] E Niv et al.. Nutr Metab (Lond). 2016. Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients with irritable bowel syndrome. doi:10.1186/s12986-016-0070-5 PubMed
- [7] Eleonora Giannetti et al.. J Pediatr Gastroenterol Nutr. 2016. Probiotics for Irritable Bowel Syndrome: Clinical Data in Children. doi:10.1097/MPG.0000000000001220 PubMed
- [8] Luigi Russo et al.. Saudi J Gastroenterol. 2015. Partially hydrolyzed guar gum in the treatment of irritable bowel syndrome with constipation: effects of gender, age, and body mass … doi:10.4103/1319-3767.153835 PubMed
- [9] Claudio Romano et al.. World J Gastroenterol. 2013. Partially hydrolyzed guar gum in pediatric functional abdominal pain. doi:10.3748/wjg.v19.i2.235 PubMed
- [10] G Quartarone. Minerva Gastroenterol Dietol. 2013. Role of PHGG as a dietary fiber: a review article. PubMed
- [11] Edoardo G Giannini et al.. Nutrition. 2006. Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome. doi:10.1016/j.nut.2005.10.003 PubMed
- [12] Giancarlo Parisi et al.. Dig Dis Sci. 2005. Treatment effects of partially hydrolyzed guar gum on symptoms and quality of life of patients with irritable bowel syndrome. A … doi:10.1007/s10620-005-2713-7 PubMed
- [13] Joanne L Slavin et al.. Nutrition. 2003. Partially hydrolyzed guar gum: clinical nutrition uses. doi:10.1016/s0899-9007(02)01032-8 PubMed
- [14] G C Parisi et al.. Dig Dis Sci. 2002. High-fiber diet supplementation in patients with irritable bowel syndrome (IBS): a multicenter, randomized, open trial comparison between wheat bran diet … doi:10.1023/a:1016419906546 PubMed
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