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Vitamin D के लिए Irritable Bowel Syndrome (IBS)

C

Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.

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निष्कर्ष

Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.

Key Study Findings

Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None बनाम: None Outcome: IBS symptom improvement with vitamin D supplementation प्रभाव: None None

जनसंख्या: individuals with irritable bowel syndrome

Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None बनाम: Various Outcome: IBS symptom improvement प्रभाव: Probiotics abdominal pain RR 4.04 (2.36-6.92) None

जनसंख्या: Adult IBS patients

Meta-Analysis Double-blind
The effects of vitamin D intake and status on symptom severity and quality-of-life in adults …
Dose: 3,000 IU daily to 50,000 IU bi-weekly बनाम: Placebo Outcome: IBS symptom severity and quality of life प्रभाव: MD 20.33 ng/mL [12.91, 27.74] for 25(OH)D; QoL 3.1 None

जनसंख्या: Adults with IBS and deficient/insufficient vitamin D

Review
Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical review.
Dose: None बनाम: None Outcome: Risk of developing Parkinson's disease प्रभाव: None None

जनसंख्या: General population (narrative review of PD risk factors)

Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None बनाम: None Outcome: Micronutrient deficiency management in pediatric IBD प्रभाव: None None

जनसंख्या: Children with inflammatory bowel disease (review)

Review
Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
Dose: None बनाम: None Outcome: IBS symptom relief and pathophysiology modulation प्रभाव: None None

जनसंख्या: Patients with irritable bowel syndrome (review)

Key Statistics

3

अध्ययन

400

प्रतिभागी

Positive

C

ग्रेड

Referenced Papers

Scandinavian journal of … 2025
Journal of gastroenterology … 2023 16 उद्धरण
World journal of … 2023 9 उद्धरण
Journal of gastroenterology … 2022 30 उद्धरण
Journal of gastroenterology … 2022 29 उद्धरण
Journal of gastroenterology … 2022 4 उद्धरण
Journal of gastroenterology … 2021 10 उद्धरण
The journal of … 2020 294 उद्धरण
Osteoporosis international : … 2020 14 उद्धरण
Current gastroenterology reports 2017 157 उद्धरण
PloS one 2017 38 उद्धरण
World journal of … 2016 238 उद्धरण
Digestive diseases (Basel, … 2016 41 उद्धरण
Clinics in dermatology 2016 19 उद्धरण
World journal of … 2015 62 उद्धरण
Oman medical journal 2015 56 उद्धरण
European journal of … 2012 225 उद्धरण
Inflammatory bowel diseases 2012 224 उद्धरण
The Cochrane database … 2012 130 उद्धरण
Current opinion in … 2011 23 उद्धरण

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

general:
600-800 IU/day (RDA)
ibdsupport:
1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
deficiencycorrection:
50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance

अधिकतम सीमा: 4,000 IU/day (100 mcg); higher doses under medical supervision only

अनुसंधान में अध्ययन की गई खुराकें

खुराक अवधि प्रभाव N
None -- Positive --
None -- Positive --
3,000 IU daily to 50,000 IU bi-weekly -- Positive --
None -- Mixed --
None -- Neutral --
None -- Positive --
None -- Positive --
None -- Positive 240

सेवन का सर्वोत्तम समय: With a meal containing fat for better absorption

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

  • Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
  • Kidney stones with excessive long-term supplementation
  • Constipation
  • Metallic taste

ज्ञात अंतःक्रियाएँ

  • Thiazide diuretics (may increase risk of hypercalcemia)
  • Corticosteroids (reduce vitamin D absorption and metabolism)
  • Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
  • Statins (vitamin D may affect statin metabolism)

सहनीय अधिकतम सेवन: 4,000 IU/day (100 mcg); higher doses under medical supervision only

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Vitamin D help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 400 participants, there is limited but promising evidence that Vitamin D may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Vitamin D should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

Vitamin D अन्य स्वास्थ्य स्थितियों के लिए

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।