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Partially Hydrolyzed Guar Gum (PHGG) для Irritable Bowel Syndrome (IBS)

B

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

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B

Итог

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

Key Study Findings

Randomized Controlled Trial n=47 8 weeks Double-blind
Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and …
Dose: None или: Placebo (Group I) and partial formulation (Group II) Outcome: IBS quality of life (QoL questionnaire) Эффект: Dysphoria: median diff -5 (Group III) vs -1 (contr 0.0021 (dysphoria Group III)

Популяция: Patients with IBS

Controlled Clinical Trial
Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable …
Dose: Partially hydrolyzed guar gum (PHGG) или: Drug therapy alone Outcome: Gut bacteria ratios and inflammatory markers Эффект: None None

Популяция: Patients with IBD or IBS on drug therapy

Controlled Clinical Trial 12.9 weeks
Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel …
Dose: None или: baseline Outcome: IBS symptom improvement Эффект: None None

Популяция: Ibs undertook a 90-day intervention and follow-up

Case Reports
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Randomized Controlled Trial 13.0 weeks Double-blind
Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: …
Dose: None или: Placebo Outcome: Bowel function Эффект: None p=0.05

Популяция: healthy volunteers

Randomized Controlled Trial 12 weeks
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients …
Dose: partially hydrolyzed guar gum (PHGG) 5g/day или: placebo Outcome: IBS-SSS and bloating severity Эффект: significant improvement in overall IBS-SSS <0.05

Популяция: Adults with IBS

Key Statistics

5

Исследования

350

Участники

Positive

B

Оценка

Referenced Papers

Journal of pediatric … 2016 19 цитирований
World journal of … 2013 69 цитирований
Minerva gastroenterologica e … 2013
Nutrition (Burbank, Los … 2006 119 цитирований
Nutrition (Burbank, Los … 2003 143 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
5-7 g/day
ibssupport:
5 g/day for 4-12 weeks
siboadjunct:
5 g/day alongside antimicrobial therapy

Верхний предел: Well-tolerated up to 36 g/day in clinical trials

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None 8 weeks Positive 47
Partially hydrolyzed guar gum (PHGG) -- Positive --
None 12.9 weeks Positive --
None -- Positive --
None 13.0 weeks Mixed --
partially hydrolyzed guar gum (PHGG) 5g/day 12 weeks Positive --
various probiotic strains -- Mixed --
None 4.0 weeks Positive --

Лучшее время приёма: Mixed into food or beverages; dissolves completely without altering texture

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Minimal gas and bloating (significantly less than other fibers)
  • Mild abdominal discomfort in rare cases
  • Loose stools at very high doses

Известные взаимодействия

  • May slow absorption of some medications (space 1-2 hours)
  • Diabetes medications (may modestly affect blood glucose)

Допустимый верхний уровень потребления: Well-tolerated up to 36 g/day in clinical trials

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Partially Hydrolyzed Guar Gum (PHGG) help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 350 participants, there is moderate evidence from clinical studies that Partially Hydrolyzed Guar Gum (PHGG) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Partially Hydrolyzed Guar Gum (PHGG) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 5-7 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Partially Hydrolyzed Guar Gum (PHGG)?
Reported side effects may include Minimal gas and bloating (significantly less than other fibers), Mild abdominal discomfort in rare cases, Loose stools at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Partially Hydrolyzed Guar Gum (PHGG) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Related Evidence

Partially Hydrolyzed Guar Gum (PHGG) для других состояний

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.