Partially Hydrolyzed Guar Gum (PHGG) ： Irritable Bowel Syndrome (IBS)
B エビデンス 少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.
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B
結論
Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.
Key Study Findings
Randomized Controlled Trial
n=47
8 weeks
Double-blind
Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and …
Dose: None
vs: Placebo (Group I) and partial formulation (Group II)
Outcome: IBS quality of life (QoL questionnaire)
効果: Dysphoria: median diff -5 (Group III) vs -1 (contr
0.0021 (dysphoria Group III)
対象集団: Patients with IBS
Controlled Clinical Trial
Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable …
Dose: Partially hydrolyzed guar gum (PHGG)
vs: Drug therapy alone
Outcome: Gut bacteria ratios and inflammatory markers
効果: None
None
対象集団: Patients with IBD or IBS on drug therapy
Controlled Clinical Trial
12.9 weeks
Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel …
Dose: None
vs: baseline
Outcome: IBS symptom improvement
効果: None
None
対象集団: Ibs undertook a 90-day intervention and follow-up
Case Reports
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: None
Randomized Controlled Trial
13.0 weeks
Double-blind
Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: …
Dose: None
vs: Placebo
Outcome: Bowel function
効果: None
p=0.05
対象集団: healthy volunteers
Randomized Controlled Trial
12 weeks
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients …
Dose: partially hydrolyzed guar gum (PHGG) 5g/day
vs: placebo
Outcome: IBS-SSS and bloating severity
効果: significant improvement in overall IBS-SSS
<0.05
対象集団: Adults with IBS
Key Statistics
5
研究数
350
参加者数
↑
Positive
B
グレード
Referenced Papers
Frontiers in nutrition
2025
3 件の引用
The journal of …
2024
2 件の引用
Nutrients
2023
3 件の引用
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Case Report
Expert review of …
2021
7 件の引用
Nutrients
2019
68 件の引用
Nutrition & metabolism
2016
61 件の引用
Probiotics for Irritable Bowel Syndrome: Clinical Data in Children.
Systematic Review
Journal of pediatric …
2016
19 件の引用
Saudi journal of …
2015
32 件の引用
World journal of …
2013
69 件の引用
Minerva gastroenterologica e …
2013
Nutrition (Burbank, Los …
2006
119 件の引用
Digestive diseases and …
2005
55 件の引用
Nutrition (Burbank, Los …
2003
143 件の引用
Digestive diseases and …
2002
117 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 5-7 g/day
- ibssupport:
- 5 g/day for 4-12 weeks
- siboadjunct:
- 5 g/day alongside antimicrobial therapy
上限量： Well-tolerated up to 36 g/day in clinical trials
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | 8 weeks | Positive | 47 |
| Partially hydrolyzed guar gum (PHGG) | -- | Positive | -- |
| None | 12.9 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | 13.0 weeks | Mixed | -- |
| partially hydrolyzed guar gum (PHGG) 5g/day | 12 weeks | Positive | -- |
| various probiotic strains | -- | Mixed | -- |
| None | 4.0 weeks | Positive | -- |
推奨摂取タイミング： Mixed into food or beverages; dissolves completely without altering texture
Safety & Side Effects
報告されている副作用
- ⚠ Minimal gas and bloating (significantly less than other fibers)
- ⚠ Mild abdominal discomfort in rare cases
- ⚠ Loose stools at very high doses
既知の相互作用
- ● May slow absorption of some medications (space 1-2 hours)
- ● Diabetes medications (may modestly affect blood glucose)
耐容上限摂取量： Well-tolerated up to 36 g/day in clinical trials
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Partially Hydrolyzed Guar Gum (PHGG) help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 350 participants, there is moderate evidence from clinical studies that Partially Hydrolyzed Guar Gum (PHGG) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Partially Hydrolyzed Guar Gum (PHGG) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 5-7 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Partially Hydrolyzed Guar Gum (PHGG)?
Reported side effects may include Minimal gas and bloating (significantly less than other fibers), Mild abdominal discomfort in rare cases, Loose stools at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Partially Hydrolyzed Guar Gum (PHGG) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： Irritable Bowel Syndrome (IBS)
Partially Hydrolyzed Guar Gum (PHGG) 他の症状・状態について
References
- [1] Adrianna Wierzbicka et al.. Front Nutr. 2025. Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients … doi:10.3389/fnut.2025.1603011 PubMed
- [2] Hideo Watanabe et al.. J Med Invest. 2024. Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable bowel syndrome induced by the … doi:10.2152/jmi.71.121 PubMed
- [3] Jerry Zhou et al.. Nutrients. 2023. Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel Syndrome. doi:10.3390/nu15224786 PubMed
- [4] Claudio Romano et al.. Expert Rev Gastroenterol Hepatol. 2021. Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases. doi:10.1080/17474124.2021.1884543 PubMed
- [5] Zenta Yasukawa et al.. Nutrients. 2019. Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled, and … doi:10.3390/nu11092170 PubMed
- [6] E Niv et al.. Nutr Metab (Lond). 2016. Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients with irritable bowel syndrome. doi:10.1186/s12986-016-0070-5 PubMed
- [7] Eleonora Giannetti et al.. J Pediatr Gastroenterol Nutr. 2016. Probiotics for Irritable Bowel Syndrome: Clinical Data in Children. doi:10.1097/MPG.0000000000001220 PubMed
- [8] Luigi Russo et al.. Saudi J Gastroenterol. 2015. Partially hydrolyzed guar gum in the treatment of irritable bowel syndrome with constipation: effects of gender, age, and body mass … doi:10.4103/1319-3767.153835 PubMed
- [9] Claudio Romano et al.. World J Gastroenterol. 2013. Partially hydrolyzed guar gum in pediatric functional abdominal pain. doi:10.3748/wjg.v19.i2.235 PubMed
- [10] G Quartarone. Minerva Gastroenterol Dietol. 2013. Role of PHGG as a dietary fiber: a review article. PubMed
- [11] Edoardo G Giannini et al.. Nutrition. 2006. Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome. doi:10.1016/j.nut.2005.10.003 PubMed
- [12] Giancarlo Parisi et al.. Dig Dis Sci. 2005. Treatment effects of partially hydrolyzed guar gum on symptoms and quality of life of patients with irritable bowel syndrome. A … doi:10.1007/s10620-005-2713-7 PubMed
- [13] Joanne L Slavin et al.. Nutrition. 2003. Partially hydrolyzed guar gum: clinical nutrition uses. doi:10.1016/s0899-9007(02)01032-8 PubMed
- [14] G C Parisi et al.. Dig Dis Sci. 2002. High-fiber diet supplementation in patients with irritable bowel syndrome (IBS): a multicenter, randomized, open trial comparison between wheat bran diet … doi:10.1023/a:1016419906546 PubMed
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