Bifidobacterium bifidum 用于 Functional Dyspepsia

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

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结论

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

Key Study Findings

Controlled Clinical Trial n=54 3.0 weeks

[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with …

Dose: 350 mg vs: None Outcome: IBS symptom improvement 效果: None None

研究人群: Irritable bowel syndrome with diarrhea and antibiotic-associated diarr

Randomized Controlled Trial n=100 4 weeks Double-blind

Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in …

Dose: 100 mL/day fermented milk vs: Placebo fermented milk Outcome: GI symptom scores (m-FSSG, GSRS) 效果: None None

研究人群: Healthy Japanese adults with GI discomfort

Other 4.0 weeks

Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms …

Dose: 100 mL/day vs: None Outcome: None 效果: None None

研究人群: men

Randomized Controlled Trial Double-blind

Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or …

Dose: None vs: Placebo + eradication regimen Outcome: H. pylori eradication rate and adverse effects 效果: None None

研究人群: Adults with H. pylori infection

Key Statistics

研究数量

500

受试者

↑

Positive

等级

Referenced Papers

[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea … Other

Voprosy pitaniia 2023

Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, … RCT

Journal of dairy … 2018 51 次引用

Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal … Other

Bioscience of microbiota, … 2015 40 次引用

Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of … RCT

BMC gastroenterology 2013 70 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 1-10 billion CFU/day
dyspepsiasupport:: 1 billion CFU/day (YIT 10347 strain)

上限： Well-tolerated up to 10 billion CFU/day in clinical trials

研究中使用的剂量

剂量	持续时间	效果	N
350 mg	3.0 weeks	Positive	54
100 mL/day fermented milk	4 weeks	Positive	100
100 mL/day	4.0 weeks	Positive	--
None	--	Neutral	--

最佳服用时间： On an empty stomach or before meals

Safety & Side Effects

已报告的副作用

⚠ Mild gas and bloating during initial use
⚠ Occasional abdominal discomfort
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

已知相互作用

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (use with caution in immunocompromised patients)

可耐受最高摄入量： Well-tolerated up to 10 billion CFU/day in clinical trials

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Bifidobacterium bifidum help with Functional Dyspepsia?

Based on 4 studies with 500 participants, there is limited but promising evidence that Bifidobacterium bifidum may support Functional Dyspepsia management. Our evidence grade is C (Some Evidence).

How much Bifidobacterium bifidum should I take for Functional Dyspepsia?

Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Bifidobacterium bifidum?

Reported side effects may include Mild gas and bloating during initial use, Occasional abdominal discomfort, Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Bifidobacterium bifidum and Functional Dyspepsia?

We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Related Evidence

其他成分用于 Functional Dyspepsia

Ginger B Deglycyrrhizinated Licorice (DGL) C

快速结论

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

Evidence Strength52%

Moderate confidence

研究分析

RCT (2)Meta (0)Other (2)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于 Functional Dyspepsia

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