Bifidobacterium bifidum para Functional Dyspepsia

C Evidências Evidência limitada de estudos de pequena dimensão, mas existem alguns sinais positivos.

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

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Conclusão

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

Key Study Findings

Controlled Clinical Trial n=54 3.0 weeks

[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with …

Dose: 350 mg vs: None Outcome: IBS symptom improvement Efeito: None None

População: Irritable bowel syndrome with diarrhea and antibiotic-associated diarr

Randomized Controlled Trial n=100 4 weeks Double-blind

Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in …

Dose: 100 mL/day fermented milk vs: Placebo fermented milk Outcome: GI symptom scores (m-FSSG, GSRS) Efeito: None None

População: Healthy Japanese adults with GI discomfort

Other 4.0 weeks

Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms …

Dose: 100 mL/day vs: None Outcome: None Efeito: None None

População: men

Randomized Controlled Trial Double-blind

Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or …

Dose: None vs: Placebo + eradication regimen Outcome: H. pylori eradication rate and adverse effects Efeito: None None

População: Adults with H. pylori infection

Key Statistics

Estudos

500

Participantes

↑

Positive

Nota

Referenced Papers

[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea … Other

Voprosy pitaniia 2023

Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, … RCT

Journal of dairy … 2018 51 citações

Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal … Other

Bioscience of microbiota, … 2015 40 citações

Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of … RCT

BMC gastroenterology 2013 70 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:: 1-10 billion CFU/day
dyspepsiasupport:: 1 billion CFU/day (YIT 10347 strain)

Limite superior: Well-tolerated up to 10 billion CFU/day in clinical trials

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
350 mg	3.0 weeks	Positive	54
100 mL/day fermented milk	4 weeks	Positive	100
100 mL/day	4.0 weeks	Positive	--
None	--	Neutral	--

Melhor horário: On an empty stomach or before meals

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Mild gas and bloating during initial use
⚠ Occasional abdominal discomfort
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

Interações Conhecidas

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (use with caution in immunocompromised patients)

Ingestão máxima tolerável: Well-tolerated up to 10 billion CFU/day in clinical trials

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Bifidobacterium bifidum help with Functional Dyspepsia?

Based on 4 studies with 500 participants, there is limited but promising evidence that Bifidobacterium bifidum may support Functional Dyspepsia management. Our evidence grade is C (Some Evidence).

How much Bifidobacterium bifidum should I take for Functional Dyspepsia?

Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Bifidobacterium bifidum?

Reported side effects may include Mild gas and bloating during initial use, Occasional abdominal discomfort, Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Bifidobacterium bifidum and Functional Dyspepsia?

We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Outros ingredientes para Functional Dyspepsia

Ginger B Deglycyrrhizinated Licorice (DGL) C

Veredito Rápido

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

Evidence Strength52%

Moderate confidence

Detalhamento dos Estudos

RCT (2)Meta (0)Other (2)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Functional Dyspepsia

Saiba Mais

References

[1] V N Drozdov et al.. Vopr Pitan. 2023. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea … doi:10.33029/0042-8833-2023-92-4-92-103 PubMed
[2] A Gomi et al.. J Dairy Sci. 2018. Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, … doi:10.3168/jds.2017-13803 PubMed
[3] Yoshihisa Urita et al.. Biosci Microbiota Food Health. 2015. Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal … doi:10.12938/bmfh.2014-017 PubMed
[4] Tomás Navarro-Rodriguez et al.. BMC Gastroenterol. 2013. Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of … doi:10.1186/1471-230X-13-56 PubMed

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.

Bifidobacterium bifidum para Functional Dyspepsia

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Conclusão

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Dosagens Comumente Utilizadas

Dosagens Estudadas em Pesquisas

Safety & Side Effects

Efeitos Colaterais Relatados

Interações Conhecidas

Frequently Asked Questions

Related Evidence

Outros ingredientes para Functional Dyspepsia

References