비피도박테리움 비피덤 관련 기능성 소화불량
C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.일본 연구에서 비피도박테리움 비피덤 YIT 10347이 산 관련 및 가스 관련 소화불량 증상을 개선했습니다. 서구 인구에서는 결과가 혼재되어 있습니다.
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C
결론
일본 연구에서 비피도박테리움 비피덤 YIT 10347이 산 관련 및 가스 관련 소화불량 증상을 개선했습니다. 서구 인구에서는 결과가 혼재되어 있습니다.
Key Study Findings
Controlled Clinical Trial
n=54
3.0 weeks
[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with …
Dose: 350 mg
vs: None
Outcome: IBS symptom improvement
효과: None
None
대상 집단: Irritable bowel syndrome with diarrhea and antibiotic-associated diarr
Randomized Controlled Trial
n=100
4 weeks
Double-blind
Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in …
Dose: 100 mL/day fermented milk
vs: Placebo fermented milk
Outcome: GI symptom scores (m-FSSG, GSRS)
효과: None
None
대상 집단: Healthy Japanese adults with GI discomfort
Other
4.0 weeks
Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms …
Dose: 100 mL/day
vs: None
Outcome: None
효과: None
None
대상 집단: men
Randomized Controlled Trial
Double-blind
Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or …
Dose: None
vs: Placebo + eradication regimen
Outcome: H. pylori eradication rate and adverse effects
효과: None
None
대상 집단: Adults with H. pylori infection
Key Statistics
4
연구
500
참여자
↑
Positive
C
등급
Referenced Papers
Voprosy pitaniia
2023
Journal of dairy …
2018
51 인용
Bioscience of microbiota, …
2015
40 인용
BMC gastroenterology
2013
70 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 1-10 billion CFU/day
- dyspepsiasupport:
- 1 billion CFU/day (YIT 10347 strain)
상한량: Well-tolerated up to 10 billion CFU/day in clinical trials
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| 350 mg | 3.0 weeks | Positive | 54 |
| 100 mL/day fermented milk | 4 weeks | Positive | 100 |
| 100 mL/day | 4.0 weeks | Positive | -- |
| None | -- | Neutral | -- |
권장 복용 시간: On an empty stomach or before meals
Safety & Side Effects
보고된 부작용
- ⚠ Mild gas and bloating during initial use
- ⚠ Occasional abdominal discomfort
- ⚠ Rare loose stools
- ⚠ Very rare: bacteremia in immunocompromised individuals
알려진 상호작용
- ● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
- ● Immunosuppressants (use with caution in immunocompromised patients)
일일 최대 섭취 허용량: Well-tolerated up to 10 billion CFU/day in clinical trials
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does 비피도박테리움 비피덤 help with 기능성 소화불량?
Based on 4 studies with 500 participants, there is limited but promising evidence that 비피도박테리움 비피덤 may support 기능성 소화불량 management. Our evidence grade is C (Some Evidence).
How much 비피도박테리움 비피덤 should I take for 기능성 소화불량?
Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of 비피도박테리움 비피덤?
Reported side effects may include Mild gas and bloating during initial use, Occasional abdominal discomfort, Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for 비피도박테리움 비피덤 and 기능성 소화불량?
We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 기능성 소화불량
References
- [1] V N Drozdov et al.. Vopr Pitan. 2023. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea … doi:10.33029/0042-8833-2023-92-4-92-103 PubMed
- [2] A Gomi et al.. J Dairy Sci. 2018. Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, … doi:10.3168/jds.2017-13803 PubMed
- [3] Yoshihisa Urita et al.. Biosci Microbiota Food Health. 2015. Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal … doi:10.12938/bmfh.2014-017 PubMed
- [4] Tomás Navarro-Rodriguez et al.. BMC Gastroenterol. 2013. Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of … doi:10.1186/1471-230X-13-56 PubMed
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