Bifidobacterium bifidum untuk Functional Dyspepsia

C Bukti Bukti terbatas dari studi kecil, namun beberapa sinyal positif ada.

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

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Kesimpulan

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

Key Study Findings

Controlled Clinical Trial n=54 3.0 weeks

[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with …

Dose: 350 mg vs: None Outcome: IBS symptom improvement Efek: None None

Populasi: Irritable bowel syndrome with diarrhea and antibiotic-associated diarr

Randomized Controlled Trial n=100 4 weeks Double-blind

Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in …

Dose: 100 mL/day fermented milk vs: Placebo fermented milk Outcome: GI symptom scores (m-FSSG, GSRS) Efek: None None

Populasi: Healthy Japanese adults with GI discomfort

Other 4.0 weeks

Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms …

Dose: 100 mL/day vs: None Outcome: None Efek: None None

Populasi: men

Randomized Controlled Trial Double-blind

Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or …

Dose: None vs: Placebo + eradication regimen Outcome: H. pylori eradication rate and adverse effects Efek: None None

Populasi: Adults with H. pylori infection

Key Statistics

Studi

500

Peserta

↑

Positive

Peringkat

Referenced Papers

[Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea … Other

Voprosy pitaniia 2023

Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, … RCT

Journal of dairy … 2018 51 sitasi

Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal … Other

Bioscience of microbiota, … 2015 40 sitasi

Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of … RCT

BMC gastroenterology 2013 70 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 1-10 billion CFU/day
dyspepsiasupport:: 1 billion CFU/day (YIT 10347 strain)

Batas atas: Well-tolerated up to 10 billion CFU/day in clinical trials

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
350 mg	3.0 weeks	Positive	54
100 mL/day fermented milk	4 weeks	Positive	100
100 mL/day	4.0 weeks	Positive	--
None	--	Neutral	--

Waktu terbaik diminum: On an empty stomach or before meals

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Mild gas and bloating during initial use
⚠ Occasional abdominal discomfort
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

Interaksi yang Diketahui

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (use with caution in immunocompromised patients)

Asupan atas yang dapat ditoleransi: Well-tolerated up to 10 billion CFU/day in clinical trials

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Bifidobacterium bifidum help with Functional Dyspepsia?

Based on 4 studies with 500 participants, there is limited but promising evidence that Bifidobacterium bifidum may support Functional Dyspepsia management. Our evidence grade is C (Some Evidence).

How much Bifidobacterium bifidum should I take for Functional Dyspepsia?

Studies have used various dosages. A commonly studied range is 1-10 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Bifidobacterium bifidum?

Reported side effects may include Mild gas and bloating during initial use, Occasional abdominal discomfort, Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Bifidobacterium bifidum and Functional Dyspepsia?

We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Bahan lain untuk Functional Dyspepsia

Ginger B Deglycyrrhizinated Licorice (DGL) C

Kesimpulan Singkat

B. bifidum YIT 10347 showed improvement in acid-related and gas-related dyspepsia symptoms in Japanese studies. Mixed results in Western populations.

Evidence Strength52%

Moderate confidence

Rincian Studi

RCT (2)Meta (0)Other (2)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Functional Dyspepsia

Pelajari Lebih Lanjut

References

[1] V N Drozdov et al.. Vopr Pitan. 2023. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea … doi:10.33029/0042-8833-2023-92-4-92-103 PubMed
[2] A Gomi et al.. J Dairy Sci. 2018. Bifidobacterium bifidum YIT 10347 fermented milk exerts beneficial effects on gastrointestinal discomfort and symptoms in healthy adults: A double-blind, randomized, … doi:10.3168/jds.2017-13803 PubMed
[3] Yoshihisa Urita et al.. Biosci Microbiota Food Health. 2015. Continuous consumption of fermented milk containing Bifidobacterium bifidum YIT 10347 improves gastrointestinal and psychological symptoms in patients with functional gastrointestinal … doi:10.12938/bmfh.2014-017 PubMed
[4] Tomás Navarro-Rodriguez et al.. BMC Gastroenterol. 2013. Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of … doi:10.1186/1471-230X-13-56 PubMed

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Bifidobacterium bifidum untuk Functional Dyspepsia

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Kesimpulan

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Dosis yang Umum Digunakan

Dosis yang Diteliti dalam Penelitian

Safety & Side Effects

Efek Samping yang Dilaporkan

Interaksi yang Diketahui

Frequently Asked Questions

Related Evidence

Bahan lain untuk Functional Dyspepsia

References