Vitamin D cho Irritable Bowel Syndrome (IBS)
C Bằng chứng Bằng chứng hạn chế từ các nghiên cứu nhỏ, nhưng có một số tín hiệu tích cực.Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
Kết luận
Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
Key Study Findings
Đối tượng nghiên cứu: individuals with irritable bowel syndrome
Đối tượng nghiên cứu: Adult IBS patients
Đối tượng nghiên cứu: Adults with IBS and deficient/insufficient vitamin D
Đối tượng nghiên cứu: General population (narrative review of PD risk factors)
Đối tượng nghiên cứu: Children with inflammatory bowel disease (review)
Đối tượng nghiên cứu: Patients with irritable bowel syndrome (review)
Key Statistics
3
Nghiên cứu
400
Người tham gia
Positive
Xếp hạng
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Liều lượng thường dùng
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
Giới hạn trên: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Liều lượng đã nghiên cứu
| Liều lượng | Thời gian | Hiệu quả | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 3,000 IU daily to 50,000 IU bi-weekly | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 240 |
Thời điểm dùng tốt nhất: With a meal containing fat for better absorption
Safety & Side Effects
Tác dụng phụ đã được báo cáo
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
Tương tác đã biết
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
Mức hấp thụ tối đa cho phép: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
Frequently Asked Questions
Does Vitamin D help with Irritable Bowel Syndrome (IBS)?
How much Vitamin D should I take for Irritable Bowel Syndrome (IBS)?
Are there side effects of Vitamin D?
How strong is the evidence for Vitamin D and Irritable Bowel Syndrome (IBS)?
Related Evidence
Các thành phần khác cho Irritable Bowel Syndrome (IBS)
Vitamin D cho các tình trạng khác
References
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