Alpha-Galactosidase cho Irritable Bowel Syndrome (IBS)

Single study in IBS patients consuming high-FODMAP diet. May reduce gas-related symptoms from specific food triggers.

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'gutcited.com'; const params = 'ingredient\u003Dalpha\u002Dgalactosidase\u0026condition\u003Dibs'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Kết luận

Single study in IBS patients consuming high-FODMAP diet. May reduce gas-related symptoms from specific food triggers.

Key Study Findings

Review

Gastrointestinal Involvement in Anderson-Fabry Disease: A Narrative Review.

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: None

Randomized Controlled Trial Double-blind

A randomized double-blind placebo-controlled crossover pilot study: Acute effects of the enzyme α-galactosidase on gastrointestinal …

Dose: 1200 G so với: placebo Outcome: every 30 min during 7 Hiệu quả: None None

Đối tượng nghiên cứu: patients with ibs after three standardized

Randomized Controlled Trial n=31 2.0 weeks Double-blind

Increasing Symptoms in Irritable Bowel Symptoms With Ingestion of Galacto-Oligosaccharides Are Mitigated by α-Galactosidase Treatment.

Dose: 300 GALU or 150 GALU so với: Placebo (glucose) Outcome: GI symptom severity on VAS Hiệu quả: None pP0.006

Đối tượng nghiên cứu: IBS patients (Rome III, H2 producers)

Randomized Controlled Trial n=125 4 weeks Double-blind

Does oral α-galactosidase relieve irritable bowel symptoms?

Dose: alpha-galactosidase 600 GalU per meal so với: placebo Outcome: overall IBS symptom relief Hiệu quả: no significant difference vs placebo >0.05

Đối tượng nghiên cứu: IBS patients

Key Statistics

Nghiên cứu

Người tham gia

↑

Positive

Xếp hạng

Referenced Papers

Gastrointestinal Involvement in Anderson-Fabry Disease: A Narrative Review. Review

International journal of … 2021 16 trích dẫn

A randomized double-blind placebo-controlled crossover pilot study: Acute effects of the enzyme α-galactosidase on gastrointestinal symptoms in irritable bowel syndrome … RCT

Neurogastroenterology and motility 2021 4 trích dẫn

Increasing Symptoms in Irritable Bowel Symptoms With Ingestion of Galacto-Oligosaccharides Are Mitigated by α-Galactosidase Treatment. RCT

The American journal … 2018 49 trích dẫn

Does oral α-galactosidase relieve irritable bowel symptoms? RCT

Scandinavian journal of … 2016 17 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 150-300 GalU (alpha-galactosidase units) per serving of gas-producing foods
standardbeanodose:: 300 GalU (2-3 tablets) with first bite of problem food

Giới hạn trên: No established upper limit; adjust per meal as needed

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
None	--	Mixed	--
1200 G	--	Neutral	--
300 GALU or 150 GALU	2.0 weeks	Positive	31
alpha-galactosidase 600 GalU per meal	4 weeks	Neutral	125

Thời điểm dùng tốt nhất: With the first bite of gas-producing food

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Generally very well-tolerated
⚠ Rare allergic reactions to mold-derived enzyme (Aspergillus source)
⚠ May cause mild GI discomfort in rare cases

Tương tác đã biết

● Acarbose (alpha-galactosidase may counteract the blood sugar-lowering mechanism of acarbose; contraindicated for concurrent use)
● Miglitol (similar mechanism conflict as acarbose)

Mức hấp thụ tối đa cho phép: No established upper limit; adjust per meal as needed

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Alpha-Galactosidase help with Irritable Bowel Syndrome (IBS)?

Based on 1 studies with 60 participants, there is preliminary evidence that needs more research that Alpha-Galactosidase may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is D (Very Early Research).

How much Alpha-Galactosidase should I take for Irritable Bowel Syndrome (IBS)?

Studies have used various dosages. A commonly studied range is 150-300 GalU (alpha-galactosidase units) per serving of gas-producing foods. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Alpha-Galactosidase?

Reported side effects may include Generally very well-tolerated, Rare allergic reactions to mold-derived enzyme (Aspergillus source), May cause mild GI discomfort in rare cases. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Alpha-Galactosidase and Irritable Bowel Syndrome (IBS)?

We rate the evidence as Grade D (Very Early Research). This rating is based on 1 peer-reviewed studies with 60 total participants. The overall direction of effect is positive.

Related Evidence

Các thành phần khác cho Irritable Bowel Syndrome (IBS)

Peppermint Oil A Lactobacillus rhamnosus GG B Psyllium Husk B Lactobacillus plantarum B Partially Hydrolyzed Guar Gum (PHGG) B Bifidobacterium longum B

Alpha-Galactosidase cho các tình trạng khác

Bloating and Intestinal Gas B

Đánh giá nhanh

Single study in IBS patients consuming high-FODMAP diet. May reduce gas-related symptoms from specific food triggers.

Evidence Strength30%

Low confidence

Phân tích nghiên cứu

RCT (3)Meta (0)Other (0)

So sánh lựa chọn thay thế

Xem các thành phần khác so sánh như thế nào cho tình trạng này.

Xem tất cả thành phần cho Irritable Bowel Syndrome (IBS)

Tìm hiểu thêm

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.