Vitamin D per Irritable Bowel Syndrome (IBS)
CLimited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
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C
In sintesi
Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
Key Study Findings
Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None
vs: None
Outcome: IBS symptom improvement with vitamin D supplementation
Effetto: None
None
Popolazione: individuals with irritable bowel syndrome
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
vs: Various
Outcome: IBS symptom improvement
Effetto: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
Popolazione: Adult IBS patients
Meta-Analysis
Double-blind
The effects of vitamin D intake and status on symptom severity and quality-of-life in adults …
Dose: 3,000 IU daily to 50,000 IU bi-weekly
vs: Placebo
Outcome: IBS symptom severity and quality of life
Effetto: MD 20.33 ng/mL [12.91, 27.74] for 25(OH)D; QoL 3.1
None
Popolazione: Adults with IBS and deficient/insufficient vitamin D
Review
Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical review.
Dose: None
vs: None
Outcome: Risk of developing Parkinson's disease
Effetto: None
None
Popolazione: General population (narrative review of PD risk factors)
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
Effetto: None
None
Popolazione: Children with inflammatory bowel disease (review)
Review
Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
Dose: None
vs: None
Outcome: IBS symptom relief and pathophysiology modulation
Effetto: None
None
Popolazione: Patients with irritable bowel syndrome (review)
Key Statistics
3
Studi
400
Partecipanti
↑
Positive
C
Grado
Referenced Papers
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None
4 citazioni
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
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2025
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Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
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Systematic Review
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Systematic Review
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Meta-Analysis
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The Effect of Vitamin D Supplementation on the Severity of Symptoms and the Quality of Life in Irritable Bowel Syndrome …
Meta-Analysis
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2022
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Association between Serum Vitamin D and Irritable Bowel Syndrome Symptoms in a Sample of Adults.
Other
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2022
7 citazioni
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2022
4 citazioni
Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.
Systematic Review
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2021
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Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome.
Other
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10 citazioni
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Meta-Analysis
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2020
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Irritable bowel syndrome: a review of the general aspects and the potential role of vitamin D.
Review
Expert review of …
2019
33 citazioni
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2019
4 citazioni
Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what …
Systematic Review
European journal of …
2018
39 citazioni
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280 citazioni
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5 citazioni
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Dietary supplements for established atopic eczema.
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Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosaggi di uso comune
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
Limite massimo: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Dosaggi studiati nella ricerca
| Dosaggio | Durata | Effetto | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 3,000 IU daily to 50,000 IU bi-weekly | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 240 |
Momento migliore per l'assunzione: With a meal containing fat for better absorption
Safety & Side Effects
Effetti collaterali segnalati
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
Interazioni note
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
Livello di assunzione massimo tollerabile: 4,000 IU/day (100 mcg); higher doses under medical supervision only
Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
Frequently Asked Questions
Does Vitamin D help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 400 participants, there is limited but promising evidence that Vitamin D may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Vitamin D should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
Altri ingredienti per Irritable Bowel Syndrome (IBS)
Vitamin D per altre condizioni
Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.