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Aloe Vera (Inner Leaf Gel) cho Irritable Bowel Syndrome (IBS)

C

Small RCTs show modest improvement in IBS symptoms. Conflicting results; some studies show no benefit over placebo.

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Kết luận

Small RCTs show modest improvement in IBS symptoms. Conflicting results; some studies show no benefit over placebo.

Key Study Findings

Review
Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines.
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: patients with IBS (review of plant extracts including peppermint oil, Iberogast, curcumin)

Review
Natural Products for the Treatment of Irritable Bowel Syndrome.
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Patients with irritable bowel syndrome

Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None so với: Various Outcome: IBS symptom improvement Hiệu quả: Probiotics abdominal pain RR 4.04 (2.36-6.92) None

Đối tượng nghiên cứu: Adult IBS patients

Controlled Clinical Trial n=43 4 weeks
Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with …
Dose: 5 g/d so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: IBS patients

Randomized Controlled Trial n=160 Double-blind
Food supplements and diet as treatment options in irritable bowel syndrome.
Dose: None so với: Placebo Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: IBS patients

Meta-Analysis
Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.
Dose: None so với: Placebo Outcome: efficacy of Western herbal medicines in the treatment … Hiệu quả: None None

Đối tượng nghiên cứu: IBS patients

Key Statistics

3

Nghiên cứu

250

Người tham gia

Mixed

C

Xếp hạng

Referenced Papers

Neurogastroenterology and motility 2020 34 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule
ibssupport:
100 mL twice daily for 1-3 months
constipation:
100-300 mg aloe latex (short-term only, maximum 1-2 weeks)

Giới hạn trên: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
None -- Mixed --
None -- Mixed --
None -- Positive --
5 g/d 4 weeks Positive 43
None -- Positive 160
None -- Positive --
500 mg 2.0 weeks Positive --
None -- Mixed --

Thời điểm dùng tốt nhất: Before meals; aloe latex should only be used short-term for constipation

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products)
  • Electrolyte imbalance (hypokalemia) with chronic laxative use
  • Potential hepatotoxicity with long-term whole leaf consumption (rare)
  • Allergic skin reactions in sensitive individuals

Tương tác đã biết

  • Digoxin (hypokalemia from laxative use may increase digoxin toxicity)
  • Diuretics (additive potassium loss with aloe latex)
  • Diabetes medications (aloe may lower blood sugar; monitor glucose)
  • Stimulant laxatives (additive laxative effect; avoid combining)
  • Anticoagulants (theoretical interaction due to platelet effects)

Mức hấp thụ tối đa cho phép: No established UL for inner leaf gel; aloe latex (anthraquinones) should be limited to 1-2 weeks

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Aloe Vera (Inner Leaf Gel) help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 250 participants, there is limited but promising evidence that Aloe Vera (Inner Leaf Gel) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Aloe Vera (Inner Leaf Gel) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 100-200 mL aloe vera inner leaf gel/juice per day, or 300-500 mg capsule. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Aloe Vera (Inner Leaf Gel)?
Reported side effects may include Diarrhea and abdominal cramps (especially with aloe latex/whole leaf products), Electrolyte imbalance (hypokalemia) with chronic laxative use, Potential hepatotoxicity with long-term whole leaf consumption (rare), Allergic skin reactions in sensitive individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Aloe Vera (Inner Leaf Gel) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 250 total participants. The overall direction of effect is mixed.

Related Evidence

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.