Vitamin D ： Irritable Bowel Syndrome (IBS)
CLimited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
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C
結論
Limited studies suggest vitamin D supplementation may improve IBS symptoms, particularly in deficient individuals. Mechanism via VDR-mediated immune modulation.
Key Study Findings
Review
Early Evidence Indicates Vitamin D Improves Symptoms of Irritable Bowel Syndrome: Nursing Implications and Future …
Dose: None
vs: None
Outcome: IBS symptom improvement with vitamin D supplementation
効果: None
None
対象集団: individuals with irritable bowel syndrome
Systematic Review
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews …
Dose: None
vs: Various
Outcome: IBS symptom improvement
効果: Probiotics abdominal pain RR 4.04 (2.36-6.92)
None
対象集団: Adult IBS patients
Meta-Analysis
Double-blind
The effects of vitamin D intake and status on symptom severity and quality-of-life in adults …
Dose: 3,000 IU daily to 50,000 IU bi-weekly
vs: Placebo
Outcome: IBS symptom severity and quality of life
効果: MD 20.33 ng/mL [12.91, 27.74] for 25(OH)D; QoL 3.1
None
対象集団: Adults with IBS and deficient/insufficient vitamin D
Review
Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical review.
Dose: None
vs: None
Outcome: Risk of developing Parkinson's disease
効果: None
None
対象集団: General population (narrative review of PD risk factors)
Review
Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?
Dose: None
vs: None
Outcome: Micronutrient deficiency management in pediatric IBD
効果: None
None
対象集団: Children with inflammatory bowel disease (review)
Review
Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
Dose: None
vs: None
Outcome: IBS symptom relief and pathophysiology modulation
効果: None
None
対象集団: Patients with irritable bowel syndrome (review)
Key Statistics
3
研究数
400
参加者数
↑
Positive
C
グレード
Referenced Papers
Gastroenterology nursing : …
None
4 件の引用
Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical …
Systematic Review
Nutrition reviews
2025
10 件の引用
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2025
7 件の引用
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Vitamin D in Irritable Bowel Syndrome: Exploring Its Role in Symptom Relief and Pathophysiology.
Review
Nutrients
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Exploring the Role of Vitamin D and the Gut Microbiome: A Cross-Sectional Study of Individuals with Irritable Bowel Syndrome and …
Systematic Review
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Vitamin D supplementation for irritable bowel syndrome: A systematic review and meta-analysis.
Meta-Analysis
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30 件の引用
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Systematic Review
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2022
29 件の引用
The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis.
Meta-Analysis
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28 件の引用
The Effect of Vitamin D Supplementation on the Severity of Symptoms and the Quality of Life in Irritable Bowel Syndrome …
Meta-Analysis
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2022
24 件の引用
PloS one
2022
10 件の引用
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9 件の引用
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Other
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2022
7 件の引用
Journal of gastroenterology …
2022
4 件の引用
Vitamin D Supplementation and Mental Health in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Patients: A Systematic Review.
Systematic Review
Nutrients
2021
16 件の引用
Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome.
Other
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2021
10 件の引用
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2020
294 件の引用
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Meta-Analysis
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14 件の引用
Cureus
2020
10 件の引用
Irritable bowel syndrome: a review of the general aspects and the potential role of vitamin D.
Review
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2019
33 件の引用
Medicine
2019
4 件の引用
Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what …
Systematic Review
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2018
39 件の引用
Saudi journal of …
2018
38 件の引用
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2017
280 件の引用
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2017
157 件の引用
PloS one
2017
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2017
5 件の引用
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2016
238 件の引用
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2016
55 件の引用
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
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2016
41 件の引用
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2016
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62 件の引用
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2015
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Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.
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2014
38 件の引用
European journal of …
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225 件の引用
Inflammatory bowel diseases
2012
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Meta-Analysis
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130 件の引用
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22 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 600-800 IU/day (RDA)
- ibdsupport:
- 1,000-4,000 IU/day (target serum 25(OH)D >30 ng/mL)
- deficiencycorrection:
- 50,000 IU/week for 8 weeks, then 1,000-4,000 IU/day maintenance
上限量： 4,000 IU/day (100 mcg); higher doses under medical supervision only
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 3,000 IU daily to 50,000 IU bi-weekly | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 240 |
推奨摂取タイミング： With a meal containing fat for better absorption
Safety & Side Effects
報告されている副作用
- ⚠ Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion)
- ⚠ Kidney stones with excessive long-term supplementation
- ⚠ Constipation
- ⚠ Metallic taste
既知の相互作用
- ● Thiazide diuretics (may increase risk of hypercalcemia)
- ● Corticosteroids (reduce vitamin D absorption and metabolism)
- ● Orlistat and cholestyramine (reduce fat-soluble vitamin absorption)
- ● Statins (vitamin D may affect statin metabolism)
耐容上限摂取量： 4,000 IU/day (100 mcg); higher doses under medical supervision only
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Vitamin D help with Irritable Bowel Syndrome (IBS)?
Based on 3 studies with 400 participants, there is limited but promising evidence that Vitamin D may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is C (Some Evidence).
How much Vitamin D should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 600-800 IU/day (RDA). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (nausea, vomiting, weakness, confusion), Kidney stones with excessive long-term supplementation, Constipation, Metallic taste. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： Irritable Bowel Syndrome (IBS)
Vitamin D 他の症状・状態について
FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。