Ginger ： Functional Dyspepsia
B エビデンス 少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。Accelerates gastric emptying by ~25%. Reduces postprandial fullness and epigastric discomfort. 1-2 g with meals.
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B
結論
Accelerates gastric emptying by ~25%. Reduces postprandial fullness and epigastric discomfort. 1-2 g with meals.
Key Study Findings
Other
Elucidating the effects of ginger processing on Magnolia bark: A multi-platform strategy linking chemical composition …
Dose: None
vs: None
Outcome: chemical composition changes and taste modulation from ginger …
効果: None
None
対象集団: None
Other
Multi-platform analysis reveals the material basis and therapeutic mechanism of Chen Xiang Qu decoction piece …
Dose: None
vs: FD model rats without treatment
Outcome: gastrointestinal motility (gastric retention rate, small intestinal propulsion …
効果: None
None
対象集団: rats with functional dyspepsia induced by tail pinching, restraint, and irregular feeding
Controlled Clinical Trial
n=47
8 weeks
Open-label
Evaluation of Adverse Effects and Tolerability of Dietary Ginger Supplementation in Patients With Functional Dyspepsia.
Dose: 1080 mg/day in divided doses
vs: Pre-treatment baseline (single-arm, open-label)
Outcome: Adverse effects and tolerability in FD
効果: None
None
対象集団: Patients with functional dyspepsia (mean age 51.5, 78.7% female)
Review
Mechanisms of action and clinical effectiveness of herbal treatments for disorders of gut-brain interaction.
Dose: None
vs: Placebo
Outcome: GI symptoms in DGBI (FD, IBS)
効果: None
None
対象集団: Patients with functional dyspepsia and IBS (review)
Review
The effectiveness and safety of natural food and food-derived extract supplements for treating functional gastrointestinal …
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: None
Randomized Controlled Trial
n=80
12 weeks
Double-blind
Efficacy and safety of steamed ginger extract for gastric health: a randomized, double-blind, placebo-controlled multi-center …
Dose: 480 mg/day GGE03
vs: Placebo
Outcome: GSRS total score and sub-scores
効果: None
<0.001 (GSRS total, subs)
対象集団: Adults with mild to moderate functional dyspepsia
Key Statistics
4
研究数
300
参加者数
↑
Positive
B
グレード
Referenced Papers
Journal of ethnopharmacology
2026
Journal of pharmaceutical …
2026
Nutrition reviews
2025
6 件の引用
Digestive and liver …
2025
4 件の引用
Current therapeutic research, …
2025
3 件の引用
Pharmaceuticals (Basel, Switzerland)
2025
3 件の引用
Food & function
2025
1 件の引用
Saudi pharmaceutical journal …
2024
4 件の引用
Non-Chinese herbal medicines for functional dyspepsia.
Systematic Review
The Cochrane database …
2023
10 件の引用
Cureus
2023
10 件の引用
Clinical nutrition ESPEN
2022
17 件の引用
Journal of dietary …
2022
1 件の引用
Persian Herbal Medicine in Functional Dyspepsia: A Systematic Review.
Systematic Review
Current drug discovery …
2021
16 件の引用
Reviews on recent …
2021
3 件の引用
Minerva gastroenterologica e …
2020
2 件の引用
Journal of ethnopharmacology
2019
83 件の引用
Advanced pharmaceutical bulletin
2019
29 件の引用
Food science & …
2019
7 件の引用
Nutrients
2018
54 件の引用
European review for …
2016
22 件の引用
Evidence-based complementary and …
2015
63 件の引用
Minerva gastroenterologica e …
2014
8 件の引用
Food & function
2013
218 件の引用
World journal of …
2011
141 件の引用
Current gastroenterology reports
2007
34 件の引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 250 mg-1 g/day of dried ginger extract
- nauseasupport:
- 1-2 g/day in divided doses
- pregnancynausea:
- 250 mg four times daily (1 g/day; consult healthcare provider)
- dyspepsiasupport:
- 1-2 g with meals
上限量： Generally well-tolerated up to 4 g/day; 1 g/day recommended during pregnancy
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| 1080 mg/day in divided doses | 8 weeks | Positive | 47 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| 480 mg/day GGE03 | 12 weeks | Positive | 80 |
| None | -- | Mixed | -- |
| None | -- | Mixed | 828 |
推奨摂取タイミング： With meals or 30 minutes before meals for dyspepsia; any time for nausea
Safety & Side Effects
報告されている副作用
- ⚠ Heartburn and GI irritation (especially at higher doses or on empty stomach)
- ⚠ Mild blood-thinning effect at very high doses
- ⚠ Mouth and throat irritation from raw ginger
- ⚠ Diarrhea at excessive doses
既知の相互作用
- ● Anticoagulants (warfarin) and antiplatelet drugs (may enhance bleeding risk at high doses)
- ● Diabetes medications (may lower blood sugar; monitor glucose levels)
- ● Antihypertensive medications (may have additive blood pressure-lowering effects)
- ● Gallstone medications (ginger increases bile flow)
耐容上限摂取量： Generally well-tolerated up to 4 g/day; 1 g/day recommended during pregnancy
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Ginger help with Functional Dyspepsia?
Based on 4 studies with 300 participants, there is moderate evidence from clinical studies that Ginger may support Functional Dyspepsia management. Our evidence grade is B (Good Evidence).
How much Ginger should I take for Functional Dyspepsia?
Studies have used various dosages. A commonly studied range is 250 mg-1 g/day of dried ginger extract. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ginger?
Reported side effects may include Heartburn and GI irritation (especially at higher doses or on empty stomach), Mild blood-thinning effect at very high doses, Mouth and throat irritation from raw ginger, Diarrhea at excessive doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ginger and Functional Dyspepsia?
We rate the evidence as Grade B (Good Evidence). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： Functional Dyspepsia
Ginger 他の症状・状態について
References
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- [2] Zhiyan Xie et al.. J Pharm Biomed Anal. 2026. Elucidating the effects of ginger processing on Magnolia bark: A multi-platform strategy linking chemical composition to taste and bioactivity. doi:10.1016/j.jpba.2026.117333 PubMed
- [3] Tianxu Liu et al.. Nutr Rev. 2025. The effectiveness and safety of natural food and food-derived extract supplements for treating functional gastrointestinal disorders-current perspectives. doi:10.1093/nutrit/nuae047 PubMed
- [4] Md Moniruzzaman et al.. Dig Liver Dis. 2025. Mechanisms of action and clinical effectiveness of herbal treatments for disorders of gut-brain interaction. doi:10.1016/j.dld.2025.07.010 PubMed
- [5] Lemlem Gebremariam Aregawi et al.. Curr Ther Res Clin Exp. 2025. Evaluation of Adverse Effects and Tolerability of Dietary Ginger Supplementation in Patients With Functional Dyspepsia. doi:10.1016/j.curtheres.2025.100792 PubMed
- [6] Andrzej Chomentowski et al.. Pharmaceuticals (Basel). 2025. Polyphenols as Modulators of Gastrointestinal Motility: Mechanistic Insights from Multi-Model Studies. doi:10.3390/ph18101564 PubMed
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- [8] Salmeen D Babelghaith et al.. Saudi Pharm J. 2024. The use of complementary and alternative medicine for functional gastrointestinal disorders among the saudi population. doi:10.1016/j.jsps.2024.102084 PubMed
- [9] Germán Báez et al.. Cochrane Database Syst Rev. 2023. Non-Chinese herbal medicines for functional dyspepsia. doi:10.1002/14651858.CD013323.pub2 PubMed
- [10] Lemlem Gebremariam Aregawi et al.. Cureus. 2023. The Effect of Ginger Supplementation on the Improvement of Dyspeptic Symptoms in Patients With Functional Dyspepsia. doi:10.7759/cureus.46061 PubMed
- [11] Zoe Martin et al.. Clin Nutr ESPEN. 2022. What is the efficacy of dietary, nutraceutical, and probiotic interventions for the management of gastroesophageal reflux disease symptoms? A systematic … doi:10.1016/j.clnesp.2022.09.015 PubMed
- [12] Sanjib Kumar Panda MPharm et al.. J Diet Suppl. 2022. A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Comparative Clinical Study to Evaluate the Efficacy and Safety of OLNP-06 versus Placebo in … doi:10.1080/19390211.2020.1856996 PubMed
- [13] Maryam Azimi et al.. Curr Drug Discov Technol. 2021. Persian Herbal Medicine in Functional Dyspepsia: A Systematic Review. doi:10.2174/1570163817666200611132831 PubMed
- [14] Antonio Tursi et al.. Rev Recent Clin Trials. 2021. Effectiveness and Safety of A Nutraceutical Formulation for the Treatment of Functional Dyspepsia in Primary Care. doi:10.2174/1574887116666210612034911 PubMed
- [15] Francesco Di Pierro et al.. Minerva Gastroenterol Dietol. 2020. Effectiveness of a nutraceutical supplement containing highly standardized perilla and ginger extracts in patients with functional dyspepsia. doi:10.23736/S1121-421X.19.02650-3 PubMed
- [16] Timo A Thumann et al.. J Ethnopharmacol. 2019. The role of gut microbiota for the activity of medicinal plants traditionally used in the European Union for gastrointestinal disorders. doi:10.1016/j.jep.2019.112153 PubMed
- [17] Vahideh Ebrahimzadeh Attari et al.. Adv Pharm Bull. 2019. The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia. doi:10.15171/apb.2019.038 PubMed
- [18] Ling-Yun Zhong et al.. Food Sci Nutr. 2019. Pharmacological effects of different ginger juices on the concurrent symptoms in animal models of functional dyspepsia: A comparative study. doi:10.1002/fsn3.990 PubMed
- [19] Amanda C Fifi et al.. Nutrients. 2018. Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials. doi:10.3390/nu10111715 PubMed
- [20] S Lazzini et al.. Eur Rev Med Pharmacol Sci. 2016. The effect of ginger (Zingiber officinalis) and artichoke (Cynara cardunculus) extract supplementation on gastric motility: a pilot randomized study in … PubMed
- [21] Attilio Giacosa et al.. Evid Based Complement Alternat Med. 2015. The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled … doi:10.1155/2015/915087 PubMed
- [22] R Pellicano et al.. Minerva Gastroenterol Dietol. 2014. Benefit of supplements in functional dyspepsia after treatment of Helicobacter pylori. PubMed
- [23] Raghavendra Haniadka et al.. Food Funct. 2013. A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe). doi:10.1039/c3fo30337c PubMed
- [24] Ming-Luen Hu et al.. World J Gastroenterol. 2011. Effect of ginger on gastric motility and symptoms of functional dyspepsia. doi:10.3748/wjg.v17.i1.105 PubMed
- [25] Maria E Perez et al.. Curr Gastroenterol Rep. 2007. Dyspepsia in childhood and adolescence: insights and treatment considerations. doi:10.1007/s11894-007-0058-4 PubMed
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