Vitamin A 用于 Acute Diarrhea
DSome evidence in vitamin A-deficient populations. WHO recommends for measles-associated diarrhea. Not effective in non-deficient individuals.
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D
结论
Some evidence in vitamin A-deficient populations. WHO recommends for measles-associated diarrhea. Not effective in non-deficient individuals.
Key Study Findings
Review
The interplay between malnutrition, persistent diarrhea, lactose intolerance, and food associated gut dysbiosis in children; …
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: children with persistent diarrhea, lactose intolerance, and gut dysbiosis in low/middle-income countries
Other
12 weeks
Revealing the mechanism of Ganoderma lucidum insoluble dietary fiber alleviating NAFLD through transcriptomics and metabolomics.
Dose: None
vs: HFD control mice
Outcome: NAFLD biomarkers and gut microbiota composition
效果: None
None
研究人群: HFD-induced NAFLD mouse model
Review
Are there Effective Vegan-Friendly Supplements for Optimizing Health and Sports Performance? a Narrative Review.
Dose: None
vs: None
Outcome: Athletic performance and nutritional optimization
效果: None
None
研究人群: Vegan athletes (narrative review)
Observational Study
Trends in burden and mortality of congenital birth defects in G20 countries (1990-2021) and predictions …
Dose: None
vs: None
Outcome: DALYs and mortality rates of congenital birth defects
效果: DALYs decreased 59.77%, deaths decreased 63.81%
None
研究人群: G20 countries population, 1990-2021
Review
B Vitamins, Glucoronolactone and the Immune System: Bioavailability, Doses and Efficiency.
Dose: B vitamins and glucuronolactone
vs: None
Outcome: Immune system function
效果: None
None
研究人群: General population (review)
Observational Study
n=48
The Resurgence of Measles Infection and its Associated Complications in Early Childhood at a Tertiary …
Dose: None
vs: None
Outcome: None
效果: None
None
研究人群: Children with acute diarrhea
Key Statistics
3
研究数量
500
受试者
↑
Positive
D
等级
Referenced Papers
BMC pediatrics
2026
BMC pregnancy and …
2025
6 次引用
Current nutrition reports
2025
3 次引用
NPJ science of …
2025
2 次引用
Nutrients
2023
21 次引用
Polish journal of …
2020
14 次引用
Brain and nerve …
2019
1 次引用
PloS one
2018
76 次引用
Interventions to reduce post-acute consequences of diarrheal disease in children: a systematic review.
Systematic Review
BMC public health
2018
23 次引用
World journal of …
2016
238 次引用
Clinics in dermatology
2016
19 次引用
Systematic reviews
2016
Maternal and child …
2015
23 次引用
Serum levels of vitamins A and D, and zinc in children with acute diarrhea: A cross-sectional study.
Other
Medical journal of …
2015
15 次引用
Vitamin and zinc status pretreatment and posttreatment in patients with inflammatory bowel disease.
Other
Journal of pediatric …
2014
38 次引用
European journal of …
2012
225 次引用
Journal of burn …
2012
16 次引用
The Journal of …
2011
30 次引用
European journal of …
2009
24 次引用
Intestinal permeability and vitamin A absorption in patients with chemotherapy-induced diarrhea.
Other
American journal of …
2008
25 次引用
Journal of pediatric …
2006
54 次引用
Acta paediatrica (Oslo, …
2004
38 次引用
Biometals : an …
2004
36 次引用
Journal of health, …
2003
The British journal …
2002
358 次引用
Pediatrics
2002
154 次引用
The British journal …
2001
74 次引用
Journal of pediatric …
2001
56 次引用
The British journal …
2001
30 次引用
Journal of tropical …
2001
8 次引用
The Journal of …
2000
107 次引用
Journal of pediatric …
2000
20 次引用
The Pediatric infectious …
2000
14 次引用
Archivos latinoamericanos de …
1999
3 次引用
Nutrition (Burbank, Los …
1998
24 次引用
The Journal of …
1998
3 次引用
"Feeding the gut": the scientific basis for continued enteral nutrition during acute diarrhea.
Review
The Journal of …
1997
48 次引用
Breast-feeding status alters the effect of vitamin A treatment during acute diarrhea in children.
RCT
The Journal of …
1997
28 次引用
The American journal …
1995
103 次引用
Indian pediatrics
1995
31 次引用
BMJ (Clinical research …
1994
105 次引用
The American journal …
1993
42 次引用
Glimpse (Dhaka, Bangladesh)
1984
The Journal of …
1983
16 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 700-900 mcg RAE/day (RDA for adults)
- gutbarriersupport:
- 900 mcg RAE/day from mixed sources
- deficiencycorrection:
- 200,000 IU single dose (WHO protocol for severe deficiency, medical supervision)
上限： 3,000 mcg RAE/day (preformed vitamin A; beta-carotene has no established UL)
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Neutral | -- |
| None | 12 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| B vitamins and glucuronolactone | -- | Positive | -- |
| None | -- | Mixed | 48 |
| None | -- | Mixed | -- |
| None | 1.0 weeks | Mixed | -- |
最佳服用时间： With meals containing fat for better absorption
Safety & Side Effects
已报告的副作用
- ⚠ Hepatotoxicity at chronic high doses of preformed vitamin A
- ⚠ Birth defects (teratogenic at high doses during pregnancy — avoid >3,000 mcg RAE/day)
- ⚠ Nausea, headache, and dizziness
- ⚠ Bone density reduction with long-term excess
已知相互作用
- ● Retinoid medications (isotretinoin, tretinoin — additive toxicity risk)
- ● Orlistat (reduces absorption of fat-soluble vitamins)
- ● Alcohol (increases hepatotoxicity risk of vitamin A)
- ● Tetracycline antibiotics (increased risk of intracranial pressure)
可耐受最高摄入量： 3,000 mcg RAE/day (preformed vitamin A; beta-carotene has no established UL)
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Vitamin A help with Acute Diarrhea?
Based on 3 studies with 500 participants, there is preliminary evidence that needs more research that Vitamin A may support Acute Diarrhea management. Our evidence grade is D (Very Early Research).
How much Vitamin A should I take for Acute Diarrhea?
Studies have used various dosages. A commonly studied range is 700-900 mcg RAE/day (RDA for adults). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin A?
Reported side effects may include Hepatotoxicity at chronic high doses of preformed vitamin A, Birth defects (teratogenic at high doses during pregnancy — avoid >3,000 mcg RAE/day), Nausea, headache, and dizziness, Bone density reduction with long-term excess. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin A and Acute Diarrhea?
We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.
Related Evidence
其他成分用于 Acute Diarrhea
Vitamin A 用于其他健康状况
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