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Partially Hydrolyzed Guar Gum (PHGG) cho Irritable Bowel Syndrome (IBS)

B

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

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B

Kết luận

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

Key Study Findings

Randomized Controlled Trial n=47 8 weeks Double-blind
Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and …
Dose: None so với: Placebo (Group I) and partial formulation (Group II) Outcome: IBS quality of life (QoL questionnaire) Hiệu quả: Dysphoria: median diff -5 (Group III) vs -1 (contr 0.0021 (dysphoria Group III)

Đối tượng nghiên cứu: Patients with IBS

Controlled Clinical Trial
Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable …
Dose: Partially hydrolyzed guar gum (PHGG) so với: Drug therapy alone Outcome: Gut bacteria ratios and inflammatory markers Hiệu quả: None None

Đối tượng nghiên cứu: Patients with IBD or IBS on drug therapy

Controlled Clinical Trial 12.9 weeks
Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel …
Dose: None so với: baseline Outcome: IBS symptom improvement Hiệu quả: None None

Đối tượng nghiên cứu: Ibs undertook a 90-day intervention and follow-up

Case Reports
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: None

Randomized Controlled Trial 13.0 weeks Double-blind
Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: …
Dose: None so với: Placebo Outcome: Bowel function Hiệu quả: None p=0.05

Đối tượng nghiên cứu: healthy volunteers

Randomized Controlled Trial 12 weeks
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients …
Dose: partially hydrolyzed guar gum (PHGG) 5g/day so với: placebo Outcome: IBS-SSS and bloating severity Hiệu quả: significant improvement in overall IBS-SSS <0.05

Đối tượng nghiên cứu: Adults with IBS

Key Statistics

5

Nghiên cứu

350

Người tham gia

Positive

B

Xếp hạng

Referenced Papers

Journal of pediatric … 2016 19 trích dẫn
Minerva gastroenterologica e … 2013
Nutrition (Burbank, Los … 2006 119 trích dẫn
Nutrition (Burbank, Los … 2003 143 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
5-7 g/day
ibssupport:
5 g/day for 4-12 weeks
siboadjunct:
5 g/day alongside antimicrobial therapy

Giới hạn trên: Well-tolerated up to 36 g/day in clinical trials

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
None 8 weeks Positive 47
Partially hydrolyzed guar gum (PHGG) -- Positive --
None 12.9 weeks Positive --
None -- Positive --
None 13.0 weeks Mixed --
partially hydrolyzed guar gum (PHGG) 5g/day 12 weeks Positive --
various probiotic strains -- Mixed --
None 4.0 weeks Positive --

Thời điểm dùng tốt nhất: Mixed into food or beverages; dissolves completely without altering texture

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • Minimal gas and bloating (significantly less than other fibers)
  • Mild abdominal discomfort in rare cases
  • Loose stools at very high doses

Tương tác đã biết

  • May slow absorption of some medications (space 1-2 hours)
  • Diabetes medications (may modestly affect blood glucose)

Mức hấp thụ tối đa cho phép: Well-tolerated up to 36 g/day in clinical trials

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Partially Hydrolyzed Guar Gum (PHGG) help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 350 participants, there is moderate evidence from clinical studies that Partially Hydrolyzed Guar Gum (PHGG) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Partially Hydrolyzed Guar Gum (PHGG) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 5-7 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Partially Hydrolyzed Guar Gum (PHGG)?
Reported side effects may include Minimal gas and bloating (significantly less than other fibers), Mild abdominal discomfort in rare cases, Loose stools at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Partially Hydrolyzed Guar Gum (PHGG) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Related Evidence

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.