Skip to main content
GutCited

N-Acetyl Cysteine (NAC) для Helicobacter pylori Infection

C

NAC (600-1,200 mg/day) may improve H. pylori eradication rates by disrupting biofilm. Small studies show improved eradication when combined with standard therapy.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'gutcited.com'; const params = 'ingredient\u003Dn\u002Dacetyl\u002Dcysteine\u0026condition\u003Dh\u002Dpylori'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

C

Итог

NAC (600-1,200 mg/day) may improve H. pylori eradication rates by disrupting biofilm. Small studies show improved eradication when combined with standard therapy.

Key Study Findings

In Vitro
Berberrubine inhibits Helicobacter pylori by inducing oxidative stress and impairing membrane integrity.
Dose: MIC 11 μg/mL или: None Outcome: anti-Helicobacter pylori activity Эффект: None None

Популяция: None

Other
Correction to "N-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter …
Dose: None или: None Outcome: None Эффект: None None

Популяция: Published erratum (correction notice)

Review
Posttranslational modifications in Helicobacter pylori-associated gastric pathogenesis: Bridging inflammation and carcinogenesis.
Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Other
Liposomal Drug Delivery against Helicobacter pylori Using Furazolidone and N-Acetyl Cysteine in Augmented Therapy.
Dose: None или: None Outcome: Cancer outcomes Эффект: None None

Популяция: Cancer patients

In Vitro
Helicobacter pylori infection selectively attenuates endothelial function in male mice via exosomes-mediated ROS production.
Dose: None или: None Outcome: choline levels/cognition Эффект: None None

Популяция: Mice

Other
α-Lipoic Acid Inhibits Apoptosis by Suppressing the Loss of Ku Proteins in Helicobacter pylori-Infected Human …
Dose: None или: None Outcome: None Эффект: None None

Популяция: None

Key Statistics

3

Исследования

250

Участники

Positive

C

Оценка

Referenced Papers

Expert review of … 2019 85 цитирований
The Cochrane database … 2019 21 цитирований
Cell host & … 2016 101 цитирований
World journal of … 2015 21 цитирований
Journal of cancer … 2013 10 цитирований
Clinical and experimental … 2012 1 цитирований
Journal of clinical … 2011 34 цитирований
Probiotics and antimicrobial … 2010 9 цитирований
American family physician 2009
Digestive diseases and … 2004 53 цитирований
Digestive diseases and … 2004 4 цитирований
Digestive diseases and … 2003 69 цитирований
Schweizerische medizinische Wochenschrift 1994 22 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
600-1,200 mg/day in divided doses
hpyloriadjunct:
600 mg twice daily alongside standard triple therapy
antioxidantsupport:
600-900 mg/day

Верхний предел: Generally well-tolerated up to 1,800 mg/day; higher doses used in clinical settings

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
MIC 11 μg/mL -- Positive --
None -- Mixed --
None -- Mixed --
None -- Positive --
None -- Mixed --
None -- Mixed --
None -- Negative --
None -- Positive --

Лучшее время приёма: With or without food; divide doses throughout the day

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Nausea and vomiting (most common, especially at higher doses)
  • Diarrhea
  • Unpleasant sulfur taste/odor
  • Headache

Известные взаимодействия

  • Nitroglycerin (NAC may enhance vasodilatory effects; risk of hypotension)
  • Activated charcoal (may reduce NAC absorption)
  • Anticoagulants (NAC may have mild antiplatelet effects)
  • ACE inhibitors (additive hypotensive effect with nitroglycerin combination)

Допустимый верхний уровень потребления: Generally well-tolerated up to 1,800 mg/day; higher doses used in clinical settings

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does N-Acetyl Cysteine (NAC) help with Helicobacter pylori Infection?
Based on 3 studies with 250 participants, there is limited but promising evidence that N-Acetyl Cysteine (NAC) may support Helicobacter pylori Infection management. Our evidence grade is C (Some Evidence).
How much N-Acetyl Cysteine (NAC) should I take for Helicobacter pylori Infection?
Studies have used various dosages. A commonly studied range is 600-1,200 mg/day in divided doses. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of N-Acetyl Cysteine (NAC)?
Reported side effects may include Nausea and vomiting (most common, especially at higher doses), Diarrhea, Unpleasant sulfur taste/odor, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for N-Acetyl Cysteine (NAC) and Helicobacter pylori Infection?
We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Helicobacter pylori Infection

N-Acetyl Cysteine (NAC) для других состояний

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.