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Partially Hydrolyzed Guar Gum (PHGG) untuk Irritable Bowel Syndrome (IBS)

B

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

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B

Kesimpulan

Reduces both IBS-C and IBS-D symptoms. Well-tolerated prebiotic that does not cause excess gas. Also shows promise for SIBO-associated symptoms.

Key Study Findings

Randomized Controlled Trial n=47 8 weeks Double-blind
Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and …
Dose: None vs: Placebo (Group I) and partial formulation (Group II) Outcome: IBS quality of life (QoL questionnaire) Efek: Dysphoria: median diff -5 (Group III) vs -1 (contr 0.0021 (dysphoria Group III)

Populasi: Patients with IBS

Controlled Clinical Trial
Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable …
Dose: Partially hydrolyzed guar gum (PHGG) vs: Drug therapy alone Outcome: Gut bacteria ratios and inflammatory markers Efek: None None

Populasi: Patients with IBD or IBS on drug therapy

Controlled Clinical Trial 12.9 weeks
Role of Baseline Gut Microbiota on Response to Fiber Intervention in Individuals with Irritable Bowel …
Dose: None vs: baseline Outcome: IBS symptom improvement Efek: None None

Populasi: Ibs undertook a 90-day intervention and follow-up

Case Reports
Fibers in pediatric functional gastrointestinal disorders. Practical considerations from clinical cases.
Dose: None vs: None Outcome: None Efek: None None

Populasi: None

Randomized Controlled Trial 13.0 weeks Double-blind
Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: …
Dose: None vs: Placebo Outcome: Bowel function Efek: None p=0.05

Populasi: healthy volunteers

Randomized Controlled Trial 12 weeks
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients …
Dose: partially hydrolyzed guar gum (PHGG) 5g/day vs: placebo Outcome: IBS-SSS and bloating severity Efek: significant improvement in overall IBS-SSS <0.05

Populasi: Adults with IBS

Key Statistics

5

Studi

350

Peserta

Positive

B

Peringkat

Referenced Papers

Journal of pediatric … 2016 19 sitasi
Minerva gastroenterologica e … 2013
Nutrition (Burbank, Los … 2003 143 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
5-7 g/day
ibssupport:
5 g/day for 4-12 weeks
siboadjunct:
5 g/day alongside antimicrobial therapy

Batas atas: Well-tolerated up to 36 g/day in clinical trials

Dosis yang Diteliti dalam Penelitian

Dosis Durasi Efek N
None 8 weeks Positive 47
Partially hydrolyzed guar gum (PHGG) -- Positive --
None 12.9 weeks Positive --
None -- Positive --
None 13.0 weeks Mixed --
partially hydrolyzed guar gum (PHGG) 5g/day 12 weeks Positive --
various probiotic strains -- Mixed --
None 4.0 weeks Positive --

Waktu terbaik diminum: Mixed into food or beverages; dissolves completely without altering texture

Safety & Side Effects

Efek Samping yang Dilaporkan

  • Minimal gas and bloating (significantly less than other fibers)
  • Mild abdominal discomfort in rare cases
  • Loose stools at very high doses

Interaksi yang Diketahui

  • May slow absorption of some medications (space 1-2 hours)
  • Diabetes medications (may modestly affect blood glucose)

Asupan atas yang dapat ditoleransi: Well-tolerated up to 36 g/day in clinical trials

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Partially Hydrolyzed Guar Gum (PHGG) help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 350 participants, there is moderate evidence from clinical studies that Partially Hydrolyzed Guar Gum (PHGG) may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Partially Hydrolyzed Guar Gum (PHGG) should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 5-7 g/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Partially Hydrolyzed Guar Gum (PHGG)?
Reported side effects may include Minimal gas and bloating (significantly less than other fibers), Mild abdominal discomfort in rare cases, Loose stools at very high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Partially Hydrolyzed Guar Gum (PHGG) and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.

Related Evidence

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.