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Psyllium Husk cho Chronic Constipation

A

Multiple meta-analyses confirm psyllium significantly increases stool frequency (mean +2.4/week) and stool weight. Superior to placebo with NNT of 3 for constipation relief. Recommended by AGA and ACG guidelines.

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A

Kết luận

Multiple meta-analyses confirm psyllium significantly increases stool frequency (mean +2.4/week) and stool weight. Superior to placebo with NNT of 3 for constipation relief. Recommended by AGA and ACG guidelines.

Key Study Findings

Review
The role of dietary fiber in the gastrointestinal tract: when, how and why?
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Review of dietary fiber role in GI tract

Review
Dietary management of chronic constipation: a review of evidence-based strategies and clinical guidelines.
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Review of dietary management of chronic constipation

Review
The role and therapeutic effectiveness of Plantago ovata husk (psyllium husk) in the prevention and …
Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: Review of psyllium husk for constipation and diarrhea

Meta-Analysis n=410
Conservative, physical and surgical interventions for managing faecal incontinence and constipation in adults with central …
Dose: None so với: Placebo Outcome: Constipation symptoms Hiệu quả: SMD -0.62, 95% CI -1.10 to -0.14 None

Đối tượng nghiên cứu: Alzheimer's disease patients

Randomized Controlled Trial Double-blind
The effect of fiber supplementation with agave fructans or psyllium plantago in symptoms of constipation …
Dose: None so với: None Outcome: Constipation symptoms Hiệu quả: None p > 0.05

Đối tượng nghiên cứu: Constipation patients

Meta-Analysis
Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in …
Dose: Various foods, drinks, diets so với: Control diet or placebo Outcome: Stool output, transit time, symptoms, QoL Hiệu quả: None None

Đối tượng nghiên cứu: Adults with chronic constipation

Key Statistics

18

Nghiên cứu

1400

Người tham gia

Positive

A

Xếp hạng

Referenced Papers

The Medical letter … 2025
Current opinion in … 2024 2 trích dẫn
Critical reviews in … 2022 99 trích dẫn
Journal of neurogastroenterology … 2021 37 trích dẫn
Complementary therapies in … 2021 30 trích dẫn
Current opinion in … 2021 6 trích dẫn
The Medical letter … 2020
Indian journal of … 2017 50 trích dẫn
International journal of … 2016 69 trích dẫn
Digestive diseases and … 2016 28 trích dẫn
Revista espanola de … 2016 27 trích dẫn
American family physician 2015
Alimentary pharmacology & … 2014 59 trích dẫn
The American journal … 2013 421 trích dẫn
Journal of clinical … 2011 30 trích dẫn
Alimentary pharmacology & … 2011 3 trích dẫn
International journal of … 2007 375 trích dẫn
Journal of the … 2007 84 trích dẫn
Current treatment options … 2006 24 trích dẫn
Acta chirurgica Iugoslavica 2006
Der Internist 2005 5 trích dẫn
Alimentary pharmacology & … 2004 322 trích dẫn
Clinical evidence 2004
Alternative medicine review … 2002 6 trích dẫn
Diseases of the … 2001 199 trích dẫn
Health technology assessment … 1997 128 trích dẫn
Allergy proceedings : … 1990 12 trích dẫn
Gastroenterology nursing : … 1989 3 trích dẫn
Biomedicine & pharmacotherapy … 1986 4 trích dẫn
JAMA 1964

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
5-10 g/day (with adequate water)
ibssupport:
5-10 g/day (start low, titrate up over 1-2 weeks)
constipation:
10-20 g/day in divided doses with at least 240 mL water per dose

Giới hạn trên: Well-tolerated up to 30 g/day with adequate fluid intake

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
None -- Mixed --
None -- Mixed --
None -- Positive --
None -- Mixed 410
None -- Negative --
Various foods, drinks, diets -- Positive --
None -- Positive --
None 1 weeks Neutral --

Thời điểm dùng tốt nhất: With meals and a full glass of water (240 mL minimum); space 1-2 hours from medications

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • Gas and bloating (common initially; start with low dose and titrate up)
  • Esophageal/bowel obstruction if taken without adequate water (CRITICAL: always take with full glass of water)
  • Abdominal cramping at high initial doses
  • May reduce appetite (feeling of fullness)

Tương tác đã biết

  • May reduce absorption of medications if taken simultaneously (space 1-2 hours)
  • Lithium (reduced absorption)
  • Carbamazepine (reduced absorption)
  • Diabetes medications (may enhance blood sugar lowering; monitor glucose)

Mức hấp thụ tối đa cho phép: Well-tolerated up to 30 g/day with adequate fluid intake

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Psyllium Husk help with Chronic Constipation?
Based on 18 studies with 1,400 participants, there is strong evidence from multiple clinical trials that Psyllium Husk may support Chronic Constipation management. Our evidence grade is A (Strong Evidence).
How much Psyllium Husk should I take for Chronic Constipation?
Studies have used various dosages. A commonly studied range is 5-10 g/day (with adequate water). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Psyllium Husk?
Reported side effects may include Gas and bloating (common initially; start with low dose and titrate up), Esophageal/bowel obstruction if taken without adequate water (CRITICAL: always take with full glass of water), Abdominal cramping at high initial doses, May reduce appetite (feeling of fullness). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Psyllium Husk and Chronic Constipation?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 18 peer-reviewed studies with 1,400 total participants. The overall direction of effect is positive.

Related Evidence

Các thành phần khác cho Chronic Constipation

Psyllium Husk cho các tình trạng khác

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.