Psyllium Husk ： Chronic Constipation
A エビデンス 複数の大規模臨床試験が一貫して有意な効果を示しています。Multiple meta-analyses confirm psyllium significantly increases stool frequency (mean +2.4/week) and stool weight. Superior to placebo with NNT of 3 for constipation relief. Recommended by AGA and ACG guidelines.
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A
結論
Multiple meta-analyses confirm psyllium significantly increases stool frequency (mean +2.4/week) and stool weight. Superior to placebo with NNT of 3 for constipation relief. Recommended by AGA and ACG guidelines.
Key Study Findings
Review
The role of dietary fiber in the gastrointestinal tract: when, how and why?
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: Review of dietary fiber role in GI tract
Review
Dietary management of chronic constipation: a review of evidence-based strategies and clinical guidelines.
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: Review of dietary management of chronic constipation
Review
The role and therapeutic effectiveness of Plantago ovata husk (psyllium husk) in the prevention and …
Dose: None
vs: None
Outcome: None
効果: None
None
対象集団: Review of psyllium husk for constipation and diarrhea
Meta-Analysis
n=410
Conservative, physical and surgical interventions for managing faecal incontinence and constipation in adults with central …
Dose: None
vs: Placebo
Outcome: Constipation symptoms
効果: SMD -0.62, 95% CI -1.10 to -0.14
None
対象集団: Alzheimer's disease patients
Randomized Controlled Trial
Double-blind
The effect of fiber supplementation with agave fructans or psyllium plantago in symptoms of constipation …
Dose: None
vs: None
Outcome: Constipation symptoms
効果: None
p > 0.05
対象集団: Constipation patients
Meta-Analysis
Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in …
Dose: Various foods, drinks, diets
vs: Control diet or placebo
Outcome: Stool output, transit time, symptoms, QoL
効果: None
None
対象集団: Adults with chronic constipation
Key Statistics
18
研究数
1400
参加者数
↑
Positive
A
グレード
Referenced Papers
The Proceedings of …
2025
2 件の引用
Przeglad gastroenterologiczny
2025
2 件の引用
Best practice & …
2025
1 件の引用
The Medical letter …
2025
The Medical letter …
2025
Food & function
2024
8 件の引用
Journal of feline …
2024
8 件の引用
[Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review].
Systematic Review
Zeitschrift fur Gastroenterologie
2024
3 件の引用
The Cochrane database …
2024
3 件の引用
Neurogastroenterology and motility
2024
3 件の引用
Current opinion in …
2024
2 件の引用
Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in adults.
Meta-Analysis
Alimentary pharmacology & …
2024
Gut microbes
2023
143 件の引用
Dietary Fibers in Healthy Children and in Pediatric Gastrointestinal Disorders: A Practical Guide.
Review
Nutrients
2023
43 件の引用
The American journal …
2023
39 件の引用
In persons with constipation or IBS-C, kiwifruit vs. psyllium increased spontaneous bowel movements.
Other
Annals of internal …
2023
Critical reviews in …
2022
99 件の引用
The American journal …
2022
80 件の引用
Food science & …
2022
52 件の引用
Kiwifruit and Kiwifruit Extracts for Treatment of Constipation: A Systematic Review and Meta-Analysis.
Meta-Analysis
Canadian journal of …
2022
9 件の引用
Efficacy and Safety of Over-the-Counter Therapies for Chronic Constipation: An Updated Systematic Review.
Systematic Review
The American journal …
2021
62 件の引用
The American journal …
2021
47 件の引用
Journal of neurogastroenterology …
2021
37 件の引用
Complementary therapies in …
2021
30 件の引用
Current opinion in …
2021
6 件の引用
Journal of the …
2020
33 件の引用
The Medical letter …
2020
Journal of the …
2019
171 件の引用
The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls.
RCT
International journal of …
2019
162 件の引用
Clinical nutrition ESPEN
2019
64 件の引用
World journal of …
2019
14 件の引用
European review for …
2018
23 件の引用
Acta gastro-enterologica Belgica
2018
17 件の引用
Canadian journal of …
2018
2 件の引用
Journal of the …
2017
447 件の引用
Probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disorders.
Review
British journal of …
2017
145 件の引用
Indian journal of …
2017
50 件の引用
International journal of …
2016
69 件の引用
Digestive diseases and …
2016
28 件の引用
Revista espanola de …
2016
27 件の引用
American family physician
2015
Systematic review: the effect of prunes on gastrointestinal function.
Systematic Review
Alimentary pharmacology & …
2014
59 件の引用
Efficacy and complications of polyethylene glycols for treatment of constipation in children: a meta-analysis.
Meta-Analysis
Medicine
2014
19 件の引用
The American journal …
2013
421 件の引用
Journal of clinical …
2011
30 件の引用
Alimentary pharmacology & …
2011
3 件の引用
Prescrire international
2009
International journal of …
2007
375 件の引用
Journal of the …
2007
84 件の引用
Current treatment options …
2006
24 件の引用
[Plantago ovata].
Review
Acta chirurgica Iugoslavica
2006
Der Internist
2005
5 件の引用
Systematic review: the role of different types of fibre in the treatment of irritable bowel syndrome.
Systematic Review
Alimentary pharmacology & …
2004
322 件の引用
Constipation in adults.
Review
Clinical evidence
2004
Plantago ovata. (Psyllium).
Review
Alternative medicine review …
2002
6 件の引用
Diseases of the …
2001
199 件の引用
Movement disorders : …
1997
196 件の引用
Systematic review of the effectiveness of laxatives in the elderly.
Systematic Review
Health technology assessment …
1997
128 件の引用
Psyllium anaphylaxis.
Case Report
Allergy proceedings : …
1990
12 件の引用
Gastroenterology nursing : …
1989
3 件の引用
Gut
1987
153 件の引用
Biomedicine & pharmacotherapy …
1986
4 件の引用
IRRITABLE COLON.
Other
JAMA
1964
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
一般的な使用量
- general:
- 5-10 g/day (with adequate water)
- ibssupport:
- 5-10 g/day (start low, titrate up over 1-2 weeks)
- constipation:
- 10-20 g/day in divided doses with at least 240 mL water per dose
上限量： Well-tolerated up to 30 g/day with adequate fluid intake
研究で検討された用量
| 用量 | 期間 | 効果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | 410 |
| None | -- | Negative | -- |
| Various foods, drinks, diets | -- | Positive | -- |
| None | -- | Positive | -- |
| None | 1 weeks | Neutral | -- |
推奨摂取タイミング： With meals and a full glass of water (240 mL minimum); space 1-2 hours from medications
Safety & Side Effects
報告されている副作用
- ⚠ Gas and bloating (common initially; start with low dose and titrate up)
- ⚠ Esophageal/bowel obstruction if taken without adequate water (CRITICAL: always take with full glass of water)
- ⚠ Abdominal cramping at high initial doses
- ⚠ May reduce appetite (feeling of fullness)
既知の相互作用
- ● May reduce absorption of medications if taken simultaneously (space 1-2 hours)
- ● Lithium (reduced absorption)
- ● Carbamazepine (reduced absorption)
- ● Diabetes medications (may enhance blood sugar lowering; monitor glucose)
耐容上限摂取量： Well-tolerated up to 30 g/day with adequate fluid intake
サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
Frequently Asked Questions
Does Psyllium Husk help with Chronic Constipation?
Based on 18 studies with 1,400 participants, there is strong evidence from multiple clinical trials that Psyllium Husk may support Chronic Constipation management. Our evidence grade is A (Strong Evidence).
How much Psyllium Husk should I take for Chronic Constipation?
Studies have used various dosages. A commonly studied range is 5-10 g/day (with adequate water). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Psyllium Husk?
Reported side effects may include Gas and bloating (common initially; start with low dose and titrate up), Esophageal/bowel obstruction if taken without adequate water (CRITICAL: always take with full glass of water), Abdominal cramping at high initial doses, May reduce appetite (feeling of fullness). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Psyllium Husk and Chronic Constipation?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 18 peer-reviewed studies with 1,400 total participants. The overall direction of effect is positive.
Related Evidence
に関する他の成分： Chronic Constipation
Psyllium Husk 他の症状・状態について
References
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