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Psyllium Husk для Chronic Constipation

A

Multiple meta-analyses confirm psyllium significantly increases stool frequency (mean +2.4/week) and stool weight. Superior to placebo with NNT of 3 for constipation relief. Recommended by AGA and ACG guidelines.

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Итог

Multiple meta-analyses confirm psyllium significantly increases stool frequency (mean +2.4/week) and stool weight. Superior to placebo with NNT of 3 for constipation relief. Recommended by AGA and ACG guidelines.

Key Study Findings

Review
The role of dietary fiber in the gastrointestinal tract: when, how and why?
Dose: None или: None Outcome: None Эффект: None None

Популяция: Review of dietary fiber role in GI tract

Review
Dietary management of chronic constipation: a review of evidence-based strategies and clinical guidelines.
Dose: None или: None Outcome: None Эффект: None None

Популяция: Review of dietary management of chronic constipation

Review
The role and therapeutic effectiveness of Plantago ovata husk (psyllium husk) in the prevention and …
Dose: None или: None Outcome: None Эффект: None None

Популяция: Review of psyllium husk for constipation and diarrhea

Meta-Analysis n=410
Conservative, physical and surgical interventions for managing faecal incontinence and constipation in adults with central …
Dose: None или: Placebo Outcome: Constipation symptoms Эффект: SMD -0.62, 95% CI -1.10 to -0.14 None

Популяция: Alzheimer's disease patients

Randomized Controlled Trial Double-blind
The effect of fiber supplementation with agave fructans or psyllium plantago in symptoms of constipation …
Dose: None или: None Outcome: Constipation symptoms Эффект: None p > 0.05

Популяция: Constipation patients

Meta-Analysis
Systematic review and meta-analysis: Foods, drinks and diets and their effect on chronic constipation in …
Dose: Various foods, drinks, diets или: Control diet or placebo Outcome: Stool output, transit time, symptoms, QoL Эффект: None None

Популяция: Adults with chronic constipation

Key Statistics

18

Исследования

1400

Участники

Positive

A

Оценка

Referenced Papers

Best practice & … 2025 1 цитирований
The Medical letter … 2025
Current opinion in … 2024 2 цитирований
Critical reviews in … 2022 99 цитирований
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The American journal … 2021 62 цитирований
Journal of neurogastroenterology … 2021 37 цитирований
Complementary therapies in … 2021 30 цитирований
Current opinion in … 2021 6 цитирований
The Medical letter … 2020
Canadian journal of … 2018 2 цитирований
Indian journal of … 2017 50 цитирований
International journal of … 2016 69 цитирований
Digestive diseases and … 2016 28 цитирований
Revista espanola de … 2016 27 цитирований
American family physician 2015
Alimentary pharmacology & … 2014 59 цитирований
The American journal … 2013 421 цитирований
Journal of clinical … 2011 30 цитирований
Alimentary pharmacology & … 2011 3 цитирований
International journal of … 2007 375 цитирований
Journal of the … 2007 84 цитирований
Current treatment options … 2006 24 цитирований
Acta chirurgica Iugoslavica 2006
Der Internist 2005 5 цитирований
Alimentary pharmacology & … 2004 322 цитирований
Clinical evidence 2004
Alternative medicine review … 2002 6 цитирований
Diseases of the … 2001 199 цитирований
Movement disorders : … 1997 196 цитирований
Health technology assessment … 1997 128 цитирований
Allergy proceedings : … 1990 12 цитирований
Gastroenterology nursing : … 1989 3 цитирований
Biomedicine & pharmacotherapy … 1986 4 цитирований
JAMA 1964

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
5-10 g/day (with adequate water)
ibssupport:
5-10 g/day (start low, titrate up over 1-2 weeks)
constipation:
10-20 g/day in divided doses with at least 240 mL water per dose

Верхний предел: Well-tolerated up to 30 g/day with adequate fluid intake

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Mixed --
None -- Mixed --
None -- Positive --
None -- Mixed 410
None -- Negative --
Various foods, drinks, diets -- Positive --
None -- Positive --
None 1 weeks Neutral --

Лучшее время приёма: With meals and a full glass of water (240 mL minimum); space 1-2 hours from medications

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Gas and bloating (common initially; start with low dose and titrate up)
  • Esophageal/bowel obstruction if taken without adequate water (CRITICAL: always take with full glass of water)
  • Abdominal cramping at high initial doses
  • May reduce appetite (feeling of fullness)

Известные взаимодействия

  • May reduce absorption of medications if taken simultaneously (space 1-2 hours)
  • Lithium (reduced absorption)
  • Carbamazepine (reduced absorption)
  • Diabetes medications (may enhance blood sugar lowering; monitor glucose)

Допустимый верхний уровень потребления: Well-tolerated up to 30 g/day with adequate fluid intake

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Psyllium Husk help with Chronic Constipation?
Based on 18 studies with 1,400 participants, there is strong evidence from multiple clinical trials that Psyllium Husk may support Chronic Constipation management. Our evidence grade is A (Strong Evidence).
How much Psyllium Husk should I take for Chronic Constipation?
Studies have used various dosages. A commonly studied range is 5-10 g/day (with adequate water). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Psyllium Husk?
Reported side effects may include Gas and bloating (common initially; start with low dose and titrate up), Esophageal/bowel obstruction if taken without adequate water (CRITICAL: always take with full glass of water), Abdominal cramping at high initial doses, May reduce appetite (feeling of fullness). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Psyllium Husk and Chronic Constipation?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 18 peer-reviewed studies with 1,400 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Chronic Constipation

Psyllium Husk для других состояний

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.