Skip to main content
GutCited

Lactobacillus plantarum cho Irritable Bowel Syndrome (IBS)

B

Reduces abdominal pain and bloating in IBS. Multiple RCTs show significant improvement in global IBS symptom scores. Strain-specific evidence for 299v is relatively strong.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'gutcited.com'; const params = 'ingredient\u003Dlactobacillus\u002Dplantarum\u0026condition\u003Dibs'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

B

Kết luận

Reduces abdominal pain and bloating in IBS. Multiple RCTs show significant improvement in global IBS symptom scores. Strain-specific evidence for 299v is relatively strong.

Key Study Findings

Meta-Analysis n=3154
Comparative effectiveness and safety of probiotics with psychotropic potential in mental health benefits in irritable …
Dose: None so với: placebo Outcome: quality of life, depression, and anxiety in IBS … Hiệu quả: SUCRA=89.7% (B. longum for QoL); SUCRA=95.6% (probiotic combo for depression) None

Đối tượng nghiên cứu: patients with irritable bowel syndrome

Meta-Analysis
Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome.
Dose: None so với: placebo Outcome: improvement in key IBS symptoms Hiệu quả: None None

Đối tượng nghiên cứu: patients with IBS from 32 RCTs evaluating 10 probiotic strains

Other n=25 4 weeks
Effect of probiotic administration of Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 …
Dose: Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 so với: phosphate-buffered saline (PBS) Outcome: visceral hypersensitivity (abdominal withdrawal reflex scores) Hiệu quả: None p<0.05

Đối tượng nghiên cứu: female rats with water avoidance stress-induced IBS-D model

Other n=1098 8 weeks Open-label
A multicenter real-world, open-label study assessing the impact of a probiotic mixture on symptoms of …
Dose: None so với: None (single-arm open-label) Outcome: Treatment success for abdominal pain and bloating Hiệu quả: 73% pain, 81.9% bloating success at T1 <0.001

Đối tượng nghiên cứu: IBS patients from 52 Italian gastroenterologists

Other
Lactobacillus plantarum and Galacto-Oligosaccharides Synbiotic Relieve Irritable Bowel Syndrome by Reshaping Gut Microbiota and Attenuating …
Dose: 1e9 CFU/day + GOS 10 g/L so với: IBS model mice without synbiotic Outcome: IBS symptoms and colonic dysfunction Hiệu quả: None <0.05

Đối tượng nghiên cứu: C. rodentium + WAS IBS mouse model

Randomized Controlled Trial n=61 12 weeks Double-blind
Four-strain probiotic exerts a positive effect on irritable bowel syndrome symptoms occurring in inflammatory bowel …
Dose: None so với: Placebo Outcome: IBS-SSS (100-point reduction) Hiệu quả: 45% active vs 33% placebo (P=0.42) P=0.42

Đối tượng nghiên cứu: IBD patients with IBS symptoms in remission

Key Statistics

5

Nghiên cứu

800

Người tham gia

Positive

B

Xếp hạng

Referenced Papers

Central-European journal of … 2020 38 trích dẫn
Foods (Basel, Switzerland) 2019 21 trích dẫn
Polski merkuriusz lekarski … 2012 8 trích dẫn
Zeitschrift fur Gastroenterologie 2005 17 trích dẫn
Journal of clinical … 2004 205 trích dẫn
Current treatment options … 2002 5 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
10-20 billion CFU/day
ibssupport:
10 billion CFU/day (299v strain) for 4 weeks minimum

Giới hạn trên: Well-tolerated up to 20 billion CFU/day in clinical trials

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
None -- Positive 3154
None -- Positive --
Bifidobacterium animalis subsp. lactis BB-12 and Lactiplantibacillus plantarum ATCC 14917 4 weeks Positive 25
None 8 weeks Positive 1098
1e9 CFU/day + GOS 10 g/L -- Positive --
None 12 weeks Neutral 61
None -- Positive --
None -- Positive --

Thời điểm dùng tốt nhất: On an empty stomach or before meals

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • Mild gas and bloating during initial use
  • Occasional loose stools
  • Histamine-related symptoms in sensitive individuals (histamine-producing species)
  • Very rare: bacteremia in immunocompromised individuals

Tương tác đã biết

  • Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
  • Immunosuppressants (theoretical risk in immunocompromised patients)
  • Histamine-intolerance medications (L. plantarum may produce biogenic amines)

Mức hấp thụ tối đa cho phép: Well-tolerated up to 20 billion CFU/day in clinical trials

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Lactobacillus plantarum help with Irritable Bowel Syndrome (IBS)?
Based on 5 studies with 800 participants, there is moderate evidence from clinical studies that Lactobacillus plantarum may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is B (Good Evidence).
How much Lactobacillus plantarum should I take for Irritable Bowel Syndrome (IBS)?
Studies have used various dosages. A commonly studied range is 10-20 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lactobacillus plantarum?
Reported side effects may include Mild gas and bloating during initial use, Occasional loose stools, Histamine-related symptoms in sensitive individuals (histamine-producing species), Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lactobacillus plantarum and Irritable Bowel Syndrome (IBS)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 5 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.

Related Evidence

Tuyên bố miễn trừ FDA: Các tuyên bố này chưa được Cục Quản lý Thực phẩm và Dược phẩm (FDA) đánh giá. Các sản phẩm và thông tin trên trang web này không nhằm mục đích chẩn đoán, điều trị, chữa bệnh hoặc phòng ngừa bất kỳ bệnh nào. Xếp hạng bằng chứng được trình bày dựa trên phân tích của chúng tôi về nghiên cứu đã bình duyệt được công bố và không cấu thành tư vấn y khoa. Luôn tham khảo ý kiến chuyên gia y tế trước khi bắt đầu bất kỳ chế độ thực phẩm chức năng nào.