Lactobacillus acidophilus для Irritable Bowel Syndrome (IBS)
B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.Improves intestinal transit time and reduces constipation symptoms in IBS-C. Fecal pH decreases indicating improved fermentation. Best evidence for L. acidophilus NCFM strain.
Итог
Improves intestinal transit time and reduces constipation symptoms in IBS-C. Fecal pH decreases indicating improved fermentation. Best evidence for L. acidophilus NCFM strain.
Key Study Findings
Популяция: adults with non-constipated irritable bowel syndrome
Популяция: patients with irritable bowel syndrome
Популяция: IBD patients with IBS symptoms in remission
Популяция: IBS patients
Популяция: IBS patients
Популяция: Crohn's disease patients
Key Statistics
3
Исследования
350
Участники
Positive
Оценка
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Часто используемые дозировки
- general:
- 1-10 billion CFU/day
- ibssupport:
- 10 billion CFU/day for 4-8 weeks
- lactosesupport:
- 1-2 billion CFU with dairy consumption
Верхний предел: Generally well-tolerated up to 20 billion CFU/day
Дозировки, изученные в исследованиях
| Дозировка | Длительность | Эффект | N |
|---|---|---|---|
| None | 12 weeks | Positive | 200 |
| None | -- | Positive | 3154 |
| None | 12 weeks | Neutral | 61 |
| 2 g | 4 weeks | Mixed | -- |
| None | 12 weeks | Positive | -- |
| None | -- | Neutral | -- |
| 10^9 CFU L. acidophilus LA-5 + L. paracasei daily | 12 weeks | Positive | 110 |
| None | -- | Positive | -- |
Лучшее время приёма: On an empty stomach or before meals; may also be taken with dairy
Safety & Side Effects
Зарегистрированные побочные эффекты
- ⚠ Mild gas and bloating during initial use
- ⚠ Occasional loose stools
- ⚠ Rare allergic reactions in dairy-sensitive individuals (dairy-cultured strains)
- ⚠ Very rare: bacteremia in immunocompromised individuals
Известные взаимодействия
- ● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
- ● Immunosuppressants (theoretical risk in immunocompromised patients)
- ● Sulfasalazine (may affect bacterial metabolism)
Допустимый верхний уровень потребления: Generally well-tolerated up to 20 billion CFU/day
Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
Frequently Asked Questions
Does Lactobacillus acidophilus help with Irritable Bowel Syndrome (IBS)?
How much Lactobacillus acidophilus should I take for Irritable Bowel Syndrome (IBS)?
Are there side effects of Lactobacillus acidophilus?
How strong is the evidence for Lactobacillus acidophilus and Irritable Bowel Syndrome (IBS)?
Related Evidence
Другие ингредиенты для Irritable Bowel Syndrome (IBS)
References
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