Galactooligosaccharides (GOS) per Irritable Bowel Syndrome (IBS)
BReduces IBS symptoms (pain, bloating, flatulence) in dose-dependent manner. 3.5 g/day showed better results than 7 g/day (excess fermentation at higher dose).
In sintesi
Reduces IBS symptoms (pain, bloating, flatulence) in dose-dependent manner. 3.5 g/day showed better results than 7 g/day (excess fermentation at higher dose).
Key Study Findings
Popolazione: review of prebiotics, probiotics, synbiotics, postbiotics for gastrointestinal inflammation
Popolazione: IBS patients (Rome IV) who improved on FODMAP diet
Popolazione: IBS-D patients (Rome IV)
Popolazione: Adult IBS patients
Popolazione: Adults with constipation-predominant IBS
Popolazione: Laboratory food science study (no human subjects)
Key Statistics
3
Studi
400
Partecipanti
Positive
Grado
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosaggi di uso comune
- general:
- 2.5-5 g/day
- ibssupport:
- 3.5 g/day (optimal dose; higher doses may increase symptoms)
- infantgutsupport:
- 0.24-0.48 g/100 mL formula (added to infant formula)
Limite massimo: Well-tolerated up to 15 g/day; optimal dose appears to be 3.5-5 g/day
Dosaggi studiati nella ricerca
| Dosaggio | Durata | Effetto | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | 12 weeks | Negative | 45 |
| None | 4 weeks | Mixed | -- |
| None | -- | Positive | -- |
| 9.2 g/day total (4.6 g twice daily) | 8 weeks | Positive | 34 |
| None | -- | Positive | -- |
| 1e9 CFU/day + GOS 10 g/L | -- | Positive | -- |
| None | -- | Neutral | -- |
Momento migliore per l'assunzione: With meals; start with lower dose and increase gradually
Safety & Side Effects
Effetti collaterali segnalati
- ⚠ Gas and bloating (especially above 5 g/day; dose-response is U-shaped)
- ⚠ Flatulence at higher doses
- ⚠ Abdominal cramping if dose increased too quickly
- ⚠ May worsen symptoms in FODMAP-sensitive individuals
Interazioni note
- ● Other FODMAPs (cumulative fermentation in sensitive individuals)
- ● Lactose-containing products (GOS is derived from lactose; generally safe for lactose-intolerant individuals as GOS itself is lactose-free)
Livello di assunzione massimo tollerabile: Well-tolerated up to 15 g/day; optimal dose appears to be 3.5-5 g/day
Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
Frequently Asked Questions
Does Galactooligosaccharides (GOS) help with Irritable Bowel Syndrome (IBS)?
How much Galactooligosaccharides (GOS) should I take for Irritable Bowel Syndrome (IBS)?
Are there side effects of Galactooligosaccharides (GOS)?
How strong is the evidence for Galactooligosaccharides (GOS) and Irritable Bowel Syndrome (IBS)?
Related Evidence
Altri ingredienti per Irritable Bowel Syndrome (IBS)
Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.