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Deglycyrrhizinated Licorice (DGL)
Deglycyrrhizinated Licorice (DGL)

herb

别名: DGL, Deglycyrrhizinated Glycyrrhiza glabra, GutGard, DGL Licorice

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About

Deglycyrrhizinated licorice (DGL) is a specially processed form of licorice root with the glycyrrhizin compound removed to prevent aldosterone-like side effects (hypertension, hypokalemia). DGL may help stimulate mucus and bicarbonate secretion in the gastric lining and enhance prostaglandin E2 production, which supports mucosal integrity. Research suggests it may support digestive comfort in functional dyspepsia and provide protective support for the gastric lining.

How It Works

Stimulates mucus and bicarbonate secretion in the gastric lining strengthening the mucosal defense barrier; enhances prostaglandin E2 production protecting mucosal integrity; promotes epithelial cell proliferation supporting mucosal repair; glycyrrhizin removed to prevent mineralocorticoid side effects.

Evidence For Conditions

健康状况 等级 研究数量 受试者
Functional Dyspepsia C 3 200 查看 →
Peptic Ulcer Disease C 2 150 查看 →

Side Effects

  • Generally very well-tolerated (glycyrrhizin removal reduces risk of major side effects)
  • Mild nausea in rare cases
  • Headache (uncommon)
  • If glycyrrhizin is NOT fully removed: hypertension, hypokalemia, edema (ensure true DGL product)

Drug & Supplement Interactions

  • Digoxin (if residual glycyrrhizin present, hypokalemia may increase digoxin toxicity)
  • Diuretics (if residual glycyrrhizin, additive potassium loss)
  • Corticosteroids (if residual glycyrrhizin, additive mineralocorticoid effects)
  • Warfarin (theoretical interaction if residual glycyrrhizin affects metabolism)

请务必告知您的医疗保健提供者您正在服用的所有补充剂。

Related Ingredients

FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。