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Slippery Elm 用于 Irritable Bowel Syndrome (IBS)

D

Single pilot study in IBS-C showed modest improvement. Traditional use is extensive but clinical evidence is extremely limited.

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            D

        

        

            
结论

            
            
Single pilot study in IBS-C showed modest improvement. Traditional use is extensive but clinical evidence is extremely limited.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Controlled Clinical Trial
                
                
                n=43
                
                
                4 weeks
                
                
            

            
                Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with …
            
            

                
                Dose: 5 g/d
                
                
                vs: None
                
                
                Outcome: None
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: IBS patients

            
        

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=31
                
                
                
                Open-label
                
            

            
                Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: pain
                
                
                效果: None
                
                
                p = 0.027
                
            

            
            
研究人群: IBS patients

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
1

        
研究数量

    

    

        
40

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders.
                        
                        
                            
                                CCT
                            
                            
                            
                        
                    

                    

                        Nutrition research (New …
                        2020
                        
                        42 次引用
                        
                    

                

                
                

                    

                        
                            Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Journal of alternative …
                        2010
                        
                        25 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
400-800 mg bark powder 3 times daily, or 5 mL tincture 3 times daily

                    

                    
                    

                        
gerdsupport:

                        
Mix 1-2 tablespoons powder in water, drink before meals

                    

                    
                    

                        
throatsoothing:

                        
Lozenges as needed

                    

                    
                

                
                

                    上限： Not established; traditional use up to 2,400 mg/day bark powder
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                5 g/d
                                4 weeks
                                
                                    
                                    Positive
                                    
                                
                                43
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                31
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： Before meals or between meals; space 1-2 hours from medications
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            May slow absorption of oral medications due to mucilage coating (space 1-2 hours)
                        
    • 
                        
                        
  • 
                            ⚠
                            Rare allergic reactions (contact dermatitis reported)
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild nausea in some individuals
                        
    • 
                        
                        
  • 
                            ⚠
                            Potential for contaminants in unregulated products
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            May reduce absorption of oral medications by coating the GI tract (space 1-2 hours from all oral meds)
                        
    • 
                        
                        
  • 
                            ●
                            No significant pharmacological interactions known
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not established; traditional use up to 2,400 mg/day bark powder
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Slippery Elm help with Irritable Bowel Syndrome (IBS)?
            
        
        

            Based on 1 studies with 40 participants, there is preliminary evidence that needs more research that Slippery Elm may support Irritable Bowel Syndrome (IBS) management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Slippery Elm should I take for Irritable Bowel Syndrome (IBS)?
            
        
        

            Studies have used various dosages. A commonly studied range is 400-800 mg bark powder 3 times daily, or 5 mL tincture 3 times daily. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Slippery Elm?
            
        
        

            Reported side effects may include May slow absorption of oral medications due to mucilage coating (space 1-2 hours), Rare allergic reactions (contact dermatitis reported), Mild nausea in some individuals, Potential for contaminants in unregulated products. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Slippery Elm and Irritable Bowel Syndrome (IBS)?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 1 peer-reviewed studies with 40 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Slippery Elm 用于其他健康状况

                    

                        
                        
                            Gastroesophageal Reflux Disease (GERD)
                            D

                        
                        
                    

                

                
            

        

        

    


    
    












    

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