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Lactobacillus reuteri für Bloating and Intestinal Gas

B

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

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B

Fazit

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

Key Study Findings

basic science
Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.
Dose: Lactobacillus reuteri E9 (dose not specified) vs.: Placebo Wirkung: None < 0.05
Observational Study n=65 Open-label
Incidence and Characterization of SIBO in NAFLD Patients.
Dose: None vs.: None Outcome: SIBO prevalence in NAFLD patients Wirkung: SIBO in 37%; post-treatment 4% remained+ None

Population: Adults with NAFLD diagnosed via FibroScan

Randomized Controlled Trial n=56 15 weeks Double-blind
Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and …
Dose: 4x10^8 CFU (induction), 2x10^8 CFU (standard) vs.: Placebo Outcome: Constipation symptoms and QoL (Constipaq/CSS) Wirkung: None pP0.05

Population: Adults with functional constipation

Other n=54 Double-blind
Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, …
Dose: None vs.: Simethicone Outcome: Safety and efficacy for functional bloating Wirkung: None pP0.008

Population: Adults with functional bloating

Meta-Analysis n=3122
Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a …
Dose: None vs.: Triple therapy alone/placebo Outcome: H. pylori eradication rate and side effects Wirkung: None None

Population: Children with H. pylori infection

Randomized Controlled Trial n=101 16 weeks Double-blind
Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, …
Dose: L. reuteri DSM 17938 (1e8 CFU twice daily) vs.: placebo Outcome: abdominal pain severity (Wong-Baker FACES) Wirkung: None None

Population: Children aged 6-15 with functional abdominal pain

Key Statistics

7

Studien

500

Teilnehmer

Positive

B

Bewertung

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
100 million - 5 billion CFU/day
infantilecolic:
100 million CFU/day (DSM 17938 strain, 5 drops)
adultgisupport:
1-5 billion CFU/day

Obergrenze: Well-tolerated up to 10 billion CFU/day in clinical trials

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
Lactobacillus reuteri E9 (dose not specified) -- Positive --
None -- Positive 65
4x10^8 CFU (induction), 2x10^8 CFU (standard) 15 weeks Positive 56
None -- Positive 54
None -- Positive 3122
L. reuteri DSM 17938 (1e8 CFU twice daily) 16 weeks Positive 101
None 4 weeks Positive --

Beste Einnahmezeit: Before meals or on empty stomach; for infants, add drops to breast milk or formula

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Mild gas in initial days of use
  • Occasional increased fussiness in infants during adjustment (transient)
  • Rare loose stools
  • Very rare: bacteremia in immunocompromised individuals

Bekannte Wechselwirkungen

  • Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
  • Immunosuppressants (theoretical risk in immunocompromised patients)
  • Proton pump inhibitors (altered gastric pH may affect colonization)

Tolerierbare Höchstaufnahmemenge: Well-tolerated up to 10 billion CFU/day in clinical trials

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Lactobacillus reuteri help with Bloating and Intestinal Gas?
Based on 7 studies with 500 participants, there is moderate evidence from clinical studies that Lactobacillus reuteri may support Bloating and Intestinal Gas management. Our evidence grade is B (Good Evidence).
How much Lactobacillus reuteri should I take for Bloating and Intestinal Gas?
Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lactobacillus reuteri?
Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lactobacillus reuteri and Bloating and Intestinal Gas?
We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Related Evidence

FDA-Haftungsausschluss: Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.