Lactobacillus reuteri per Bloating and Intestinal Gas

Q: Does Lactobacillus reuteri help with Bloating and Intestinal Gas?

Based on 7 studies with 500 participants, there is moderate evidence from clinical studies that Lactobacillus reuteri may support Bloating and Intestinal Gas management. Our evidence grade is B (Good Evidence).

Q: How much Lactobacillus reuteri should I take for Bloating and Intestinal Gas?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Lactobacillus reuteri and Bloating and Intestinal Gas?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

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In sintesi

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

Key Study Findings

basic science

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.

Dose: Lactobacillus reuteri E9 (dose not specified) vs: Placebo Effetto: None < 0.05

Observational Study n=65 Open-label

Incidence and Characterization of SIBO in NAFLD Patients.

Dose: None vs: None Outcome: SIBO prevalence in NAFLD patients Effetto: SIBO in 37%; post-treatment 4% remained+ None

Popolazione: Adults with NAFLD diagnosed via FibroScan

Randomized Controlled Trial n=56 15 weeks Double-blind

Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and …

Dose: 4x10^8 CFU (induction), 2x10^8 CFU (standard) vs: Placebo Outcome: Constipation symptoms and QoL (Constipaq/CSS) Effetto: None pP0.05

Popolazione: Adults with functional constipation

Other n=54 Double-blind

Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, …

Dose: None vs: Simethicone Outcome: Safety and efficacy for functional bloating Effetto: None pP0.008

Popolazione: Adults with functional bloating

Meta-Analysis n=3122

Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a …

Dose: None vs: Triple therapy alone/placebo Outcome: H. pylori eradication rate and side effects Effetto: None None

Popolazione: Children with H. pylori infection

Randomized Controlled Trial n=101 16 weeks Double-blind

Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, …

Dose: L. reuteri DSM 17938 (1e8 CFU twice daily) vs: placebo Outcome: abdominal pain severity (Wong-Baker FACES) Effetto: None None

Popolazione: Children aged 6-15 with functional abdominal pain

Key Statistics

Studi

500

Partecipanti

↑

Positive

Grado

Referenced Papers

Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA. Other

Frontiers in bioscience … 2025

Incidence and Characterization of SIBO in NAFLD Patients. Other

Euroasian journal of … 2025

Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and bowel habit in functional constipation. RCT

Beneficial microbes 2018 35 citazioni

Efficacy and safety of APT036 versus simethicone in the treatment of functional bloating: a multicentre, randomised, double-blind, parallel group, clinical … Other

Translational gastroenterology and … 2018 24 citazioni

Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Meta-Analysis

European journal of … 2017 93 citazioni

Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, Double-Blind, Placebo-Controlled Trial. RCT

The Journal of … 2016 84 citazioni

Probiotic vs. Placebo in Irritable Bowel Syndrome:A Randomized Controlled Trial. Other

Middle East journal … 2013 13 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:: 100 million - 5 billion CFU/day
infantilecolic:: 100 million CFU/day (DSM 17938 strain, 5 drops)
adultgisupport:: 1-5 billion CFU/day

Limite massimo: Well-tolerated up to 10 billion CFU/day in clinical trials

Dosaggi studiati nella ricerca

Dosaggio	Durata	Effetto	N
Lactobacillus reuteri E9 (dose not specified)	--	Positive	--
None	--	Positive	65
4x10^8 CFU (induction), 2x10^8 CFU (standard)	15 weeks	Positive	56
None	--	Positive	54
None	--	Positive	3122
L. reuteri DSM 17938 (1e8 CFU twice daily)	16 weeks	Positive	101
None	4 weeks	Positive	--

Momento migliore per l'assunzione: Before meals or on empty stomach; for infants, add drops to breast milk or formula

Safety & Side Effects

Effetti collaterali segnalati

⚠ Mild gas in initial days of use
⚠ Occasional increased fussiness in infants during adjustment (transient)
⚠ Rare loose stools
⚠ Very rare: bacteremia in immunocompromised individuals

Interazioni note

● Antibiotics (may reduce probiotic viability; space dosing 2 hours apart)
● Immunosuppressants (theoretical risk in immunocompromised patients)
● Proton pump inhibitors (altered gastric pH may affect colonization)

Livello di assunzione massimo tollerabile: Well-tolerated up to 10 billion CFU/day in clinical trials

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Lactobacillus reuteri help with Bloating and Intestinal Gas?

Based on 7 studies with 500 participants, there is moderate evidence from clinical studies that Lactobacillus reuteri may support Bloating and Intestinal Gas management. Our evidence grade is B (Good Evidence).

How much Lactobacillus reuteri should I take for Bloating and Intestinal Gas?

Studies have used various dosages. A commonly studied range is 100 million - 5 billion CFU/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lactobacillus reuteri?

Reported side effects may include Mild gas in initial days of use, Occasional increased fussiness in infants during adjustment (transient), Rare loose stools, Very rare: bacteremia in immunocompromised individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lactobacillus reuteri and Bloating and Intestinal Gas?

We rate the evidence as Grade B (Good Evidence). This rating is based on 7 peer-reviewed studies with 500 total participants. The overall direction of effect is positive.

Related Evidence

Altri ingredienti per Bloating and Intestinal Gas

Pancreatic Enzymes (Pancrelipase) A Ginger B Alpha-Galactosidase B Medium-Chain Triglycerides (MCT Oil) C

Lactobacillus reuteri per altre condizioni

Gastroesophageal Reflux Disease (GERD) C

Verdetto rapido

Multiple RCTs in breastfed infants show reduced crying time (50-70 min/day reduction). Well-established evidence for infantile colic but limited to infant population.

Evidence Strength72%

High confidence

Analisi degli studi

RCT (2)Meta (1)Other (4)

Confronta le alternative

Scoprite come si confrontano altri ingredienti per questa condizione.

Visualizza tutti gli ingredienti per Bloating and Intestinal Gas

Approfondimenti

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.