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GutCited

Zinc
Zinc

mineral

别名: Zinc Gluconate, Zinc Picolinate, Zinc Sulfate, Zinc Acetate, Zinc Citrate

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About





            

                
锌是一种必需微量矿物质，作为肠道碱性磷酸酶的辅助因子，在肠道健康中发挥关键作用，有助于解毒细菌内毒素。锌通过促进密蛋白（claudin）的表达支持紧密连接的完整性，并参与潘氏细胞分泌抗菌肽（防御素）及黏膜免疫细胞功能的调节。世卫组织（WHO）和联合国儿童基金会（UNICEF）推荐对所有急性腹泻患儿补充锌，研究表明其可能将腹泻持续时间缩短约25%，并减少随后2至3个月内的腹泻发作次数。锌被认为有助于支持肠道健康与正常的消化免疫功能。

            

        

        

        
        
        

            

  
How It Works





            

                
Essential cofactor for intestinal alkaline phosphatase detoxifying bacterial endotoxin (LPS); maintains tight junction integrity via claudin and occludin expression; supports Paneth cell antimicrobial peptide (defensin) secretion; required for mucosal immune cell function and IgA production.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Acute Diarrhea
                                    
                                
                                
                                    A

                                
                                
                                    33
                                
                                
                                    10000
                                
                                
                                    
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Side Effects





            
    
                
                
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                    Nausea and vomiting (most common, especially on empty stomach)
                
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                    Metallic taste
                
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                    Copper depletion with long-term supplementation above 40 mg/day
                
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                    Diarrhea (paradoxically, at high doses)
                
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Drug & Supplement Interactions





            
    
                
                
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                    Tetracycline and quinolone antibiotics (zinc reduces absorption; space 2 hours)
                
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                    Penicillamine (zinc reduces absorption; space 2 hours)
                
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                    Iron supplements (mutual inhibition of absorption; take at different times)
                
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                    Copper supplements (zinc competes with copper for absorption)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Zinc Carnosine
                    
                
                
            

        

        
    


    
    












    

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