Skip to main content
GutCited

Peppermint Oil
Peppermint Oil

herb

别名: Mentha x piperita Oil, IBgard, Colpermin, Mintec

<\/script>\n
`; }, get iframeSnippet() { const domain = 'gutcited.com'; const params = 'ingredient\u003Dpeppermint\u002Doil'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    






    
    

        
        
        

            

  
About





            

                
Peppermint oil is one of the most robustly studied herbal interventions for IBS, supported by Cochrane-quality meta-analyses. Its active component, menthol, blocks calcium channels in intestinal smooth muscle to produce an antispasmodic effect and activates TRPM8 cold receptors that may help reduce visceral pain perception. Research suggests enteric-coated peppermint oil capsules may significantly reduce IBS-related abdominal pain and improve overall symptom scores.

            

        

        

        
        
        

            

  
How It Works





            

                
Menthol blocks L-type calcium channels in intestinal smooth muscle causing antispasmodic relaxation; activates TRPM8 cold receptors reducing visceral pain perception; speeds early-phase gastric emptying while reducing colonic motility; antimicrobial activity against enteric pathogens.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Irritable Bowel Syndrome (IBS)
                                    
                                
                                
                                    A

                                
                                
                                    19
                                
                                
                                    2569
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
  • 
                    
                    Heartburn/GERD exacerbation (if non-enteric-coated; relaxes lower esophageal sphincter)
                
    • 
                
                
  • 
                    
                    Perianal burning sensation (from undigested menthol reaching the rectum)
                
    • 
                
                
  • 
                    
                    Nausea at high doses
                
    • 
                
                
  • 
                    
                    Allergic reactions in mint-sensitive individuals
                
    • 
                
            

        

        

        
        
        

            

  
Drug & Supplement Interactions





            
    
                
                
  • 
                    
                    Cyclosporine (peppermint may increase cyclosporine levels via CYP3A4 inhibition)
                
    • 
                
                
  • 
                    
                    Antacids and PPIs (may dissolve enteric coating prematurely; space 2 hours)
                
    • 
                
                
  • 
                    
                    Simethicone (coated formulations may interact with enteric-coated peppermint)
                
    • 
                
                
  • 
                    
                    CYP2C19 substrates (menthol is a weak CYP inhibitor)
                
    • 
                
            

            

                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Curcumin
                    
                
                
                
                    Ginger
                    
                
                
                
                    Berberine
                    
                
                
                
                    Slippery Elm
                    
                
                
                
                    Deglycyrrhizinated Licorice (DGL)
                    
                
                
            

        

        
    


    
    












    

        FDA 免责声明:
        这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。