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Medium-Chain Triglycerides (MCT Oil) 用于 腹胀与肠胃气胀

C 证据 来自小型研究的证据有限，但存在一些积极信号。

Readily absorbed without bile acids. Beneficial in short bowel syndrome and pancreatic insufficiency for caloric supplementation. Evidence for GI symptom reduction is limited.

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            C

        

        

            
结论

            
            
Readily absorbed without bile acids. Beneficial in short bowel syndrome and pancreatic insufficiency for caloric supplementation. Evidence for GI symptom reduction is limited.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=10
                
                
                
            

            
                Open-label long-term treatment of add-on triheptanoin in adults with drug-resistant epilepsy.
            
            

                
                Dose: 1.1 mL/kg
                
                
                vs: None
                
                
                Outcome: feasibility, safety, and tolerability of long-term (48 weeks) …
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Epilepsy patients

            
        

        
        

            

                
                    Other
                
                
                
                4 weeks
                
                
            

            
                Complex Enterally Tube-Fed Community Patients Display Stable Tolerance, Improved Compliance and Better Achieve Energy and …
            
            

                
                Dose: 7.5 g
                
                
                vs: None
                
                
                Outcome: None
                
                
                效果: None
                
                
                p = 0.496
                
            

            
            
研究人群: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Dietary fat intake and functional dyspepsia.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: None
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Functional dyspepsia patients (dietary fat)

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
3

        
研究数量

    

    

        
200

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Open-label long-term treatment of add-on triheptanoin in adults with drug-resistant epilepsy.
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Epilepsia open
                        2020
                        
                        7 次引用
                        
                    

                

                
                

                    

                        
                            Complex Enterally Tube-Fed Community Patients Display Stable Tolerance, Improved Compliance and Better Achieve Energy and Protein Targets with a High-Energy, …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2020
                        
                        6 次引用
                        
                    

                

                
                

                    

                        
                            Dietary fat intake and functional dyspepsia.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Advanced biomedical research
                        2016
                        
                        26 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
5-15 mL (1-3 tablespoons) per day

                    

                    
                    

                        
malabsorptionsupport:

                        
15-30 mL per day in divided doses

                    

                    
                    

                        
antimicrobialprotocol:

                        
1-2 tablespoons per day (caprylic acid-rich MCT)

                    

                    
                

                
                

                    上限： Not established; doses above 30 mL/day commonly cause GI distress
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                1.1 mL/kg
                                --
                                
                                    
                                    Mixed
                                    
                                
                                10
                            

                            
                            

                                7.5 g
                                4 weeks
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With meals; start with small doses (1 teaspoon) and increase gradually
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Diarrhea and loose stools (most common, especially when starting; titrate dose up slowly)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea and abdominal cramping
                        
    • 
                        
                        
  • 
                            ⚠
                            Bloating
                        
    • 
                        
                        
  • 
                            ⚠
                            May raise LDL cholesterol in some individuals
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Blood sugar-lowering medications (MCTs may affect ketone and glucose metabolism)
                        
    • 
                        
                        
  • 
                            ●
                            Hepatotoxic medications (MCTs are metabolized in the liver; caution in liver disease)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not established; doses above 30 mL/day commonly cause GI distress
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Medium-Chain Triglycerides (MCT Oil) help with 腹胀与肠胃气胀?
            
        
        

            Based on 3 studies with 200 participants, there is limited but promising evidence that Medium-Chain Triglycerides (MCT Oil) may support 腹胀与肠胃气胀 management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Medium-Chain Triglycerides (MCT Oil) should I take for 腹胀与肠胃气胀?
            
        
        

            Studies have used various dosages. A commonly studied range is 5-15 mL (1-3 tablespoons) per day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Medium-Chain Triglycerides (MCT Oil)?
            
        
        

            Reported side effects may include Diarrhea and loose stools (most common, especially when starting; titrate dose up slowly), Nausea and abdominal cramping, Bloating, May raise LDL cholesterol in some individuals. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Medium-Chain Triglycerides (MCT Oil) and 腹胀与肠胃气胀?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Medium-Chain Triglycerides (MCT Oil) 用于其他健康状况

                    

                        
                        
                            肠道菌群失调
                            D

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Karin Borges et al..
      Epilepsia Open.
      2020.
      Open-label long-term treatment of add-on triheptanoin in adults with drug-resistant epilepsy.
      doi:10.1002/epi4.12391
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Benjamin Green et al..
      Nutrients.
      2020.
      Complex Enterally Tube-Fed Community Patients Display Stable Tolerance, Improved Compliance and Better Achieve Energy and Protein Targets with a High-Energy, …
      doi:10.3390/nu12113538
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Mahdieh Khodarahmi et al..
      Adv Biomed Res.
      2016.
      Dietary fat intake and functional dyspepsia.
      doi:10.4103/2277-9175.180988
      PubMed
    
    4. 
    
  















    

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